Specifically, in this experiment set, known experiment labels are:
This report contains all the functional information that was requested by the options when functional_Hunter.R was executed. The functional categories can be:
All the functional categories are computed with ClusterProfiler and GO categories are computed also with TopGo.
Some sections will not show if there are not sinficative results. Each category is analysed using Over representation analysis (ORA) and Gene Set Analysis (GSEA). The ORA method takes a group of significative DEGs (only DEGs, upregulated DEGs or downregulated DEGs) and performs a hypergeometric test for each term of the selected functional category. In the case of the GSEA method, all the genes are sorted by their fold-change and the algorithm scan which genes with similar fold-change shares a term of the selected functional category.
Statistics about input results obtained from DEGenes Expression Hunter are:
| Gene_tag | Genes |
|---|---|
| NOT_DEG | 16704 |
| POSSIBLE_DEG | 37 |
| PREVALENT_DEG | 63 |
Table of signifcant genes. Variables taken into account are being shown into table (except gene symbols/ID). Top of positive (20 items) and negative (18 items) are being shown in two different tables
| rownames | input_IDs | logFC_DESeq2 | logFC_edgeR | mean_logFCs | SYMBOL |
|---|---|---|---|---|---|
| ENSG00000107562 | ENSG00000107562 | 2.50073013395375 | 2.50589129791027 | 2.50331071593201 | CXCL12 |
| ENSG00000075223 | ENSG00000075223 | 2.56308377116416 | 2.53404815740822 | 2.54856596428619 | SEMA3C |
| ENSG00000135373 | ENSG00000135373 | 2.65118568841675 | 2.62199619589012 | 2.63659094215344 | EHF |
| ENSG00000164120 | ENSG00000164120 | 2.77190352564574 | 2.72574791320353 | 2.74882571942464 | HPGD |
| ENSG00000152207 | ENSG00000152207 | 2.78190686861342 | 2.72410161009241 | 2.75300423935292 | CYSLTR2 |
| ENSG00000166535 | ENSG00000166535 | 3.28602748954438 | 3.23761339002102 | 3.2618204397827 | A2ML1 |
| ENSG00000198848 | ENSG00000198848 | 4.89654791300351 | 5.6871371658295 | 5.2918425394165 | CES1 |
| ENSG00000227425 | ENSG00000227425 | 4.90797507515821 | 5.69191001777592 | 5.29994254646707 | NA |
| ENSG00000073754 | ENSG00000073754 | 5.05869839771353 | 5.0382064256174 | 5.04845241166547 | CD5L |
| ENSG00000163534 | ENSG00000163534 | 5.17275132262055 | 5.16057170679365 | 5.1666615147071 | FCRL1 |
| ENSG00000132704 | ENSG00000132704 | 5.20333662540855 | 5.02668368561451 | 5.11501015551153 | FCRL2 |
| ENSG00000248837 | ENSG00000248837 | 5.45459712833339 | 5.2340626269356 | 5.3443298776345 | LOC105374524 |
| ENSG00000223756 | ENSG00000223756 | 5.8137796438807 | 6.58085065215153 | 6.19731514801611 | NA |
| ENSG00000228065 | ENSG00000228065 | 5.9013462920888 | 5.67629893150035 | 5.78882261179458 | NA |
| ENSG00000249948 | ENSG00000249948 | 6.27363776230444 | 7.04452761048229 | 6.65908268639336 | GBA3 |
| ENSG00000105492 | ENSG00000105492 | 2.94168223373985 | 2.88806561540889 | 2.91487392457437 | SIGLEC6 |
| ENSG00000173218 | ENSG00000173218 | 3.11191964307186 | 2.959942454356 | 3.03593104871393 | VANGL1 |
| ENSG00000250107 | ENSG00000250107 | 3.180800473785 | 3.01850158237708 | 3.09965102808104 | CACNA1G-AS1 |
| ENSG00000128274 | ENSG00000128274 | 3.29622259074658 | 3.1243277128575 | 3.21027515180204 | A4GALT |
| ENSG00000204460 | ENSG00000204460 | 3.66131177483749 | 3.40876502389018 | 3.53503839936384 | LINC01854 |
| rownames | input_IDs | logFC_DESeq2 | logFC_edgeR | mean_logFCs | SYMBOL |
|---|---|---|---|---|---|
| ENSG00000107562 | ENSG00000107562 | 2.50073013395375 | 2.50589129791027 | 2.50331071593201 | CXCL12 |
| ENSG00000075223 | ENSG00000075223 | 2.56308377116416 | 2.53404815740822 | 2.54856596428619 | SEMA3C |
| ENSG00000135373 | ENSG00000135373 | 2.65118568841675 | 2.62199619589012 | 2.63659094215344 | EHF |
| ENSG00000164120 | ENSG00000164120 | 2.77190352564574 | 2.72574791320353 | 2.74882571942464 | HPGD |
| ENSG00000152207 | ENSG00000152207 | 2.78190686861342 | 2.72410161009241 | 2.75300423935292 | CYSLTR2 |
| ENSG00000166535 | ENSG00000166535 | 3.28602748954438 | 3.23761339002102 | 3.2618204397827 | A2ML1 |
| ENSG00000198848 | ENSG00000198848 | 4.89654791300351 | 5.6871371658295 | 5.2918425394165 | CES1 |
| ENSG00000227425 | ENSG00000227425 | 4.90797507515821 | 5.69191001777592 | 5.29994254646707 | NA |
| ENSG00000073754 | ENSG00000073754 | 5.05869839771353 | 5.0382064256174 | 5.04845241166547 | CD5L |
| ENSG00000163534 | ENSG00000163534 | 5.17275132262055 | 5.16057170679365 | 5.1666615147071 | FCRL1 |
| ENSG00000132704 | ENSG00000132704 | 5.20333662540855 | 5.02668368561451 | 5.11501015551153 | FCRL2 |
| ENSG00000248837 | ENSG00000248837 | 5.45459712833339 | 5.2340626269356 | 5.3443298776345 | LOC105374524 |
| ENSG00000223756 | ENSG00000223756 | 5.8137796438807 | 6.58085065215153 | 6.19731514801611 | NA |
| ENSG00000228065 | ENSG00000228065 | 5.9013462920888 | 5.67629893150035 | 5.78882261179458 | NA |
| ENSG00000249948 | ENSG00000249948 | 6.27363776230444 | 7.04452761048229 | 6.65908268639336 | GBA3 |
| ENSG00000105492 | ENSG00000105492 | 2.94168223373985 | 2.88806561540889 | 2.91487392457437 | SIGLEC6 |
| ENSG00000173218 | ENSG00000173218 | 3.11191964307186 | 2.959942454356 | 3.03593104871393 | VANGL1 |
| ENSG00000250107 | ENSG00000250107 | 3.180800473785 | 3.01850158237708 | 3.09965102808104 | CACNA1G-AS1 |
| ENSG00000128274 | ENSG00000128274 | 3.29622259074658 | 3.1243277128575 | 3.21027515180204 | A4GALT |
| ENSG00000204460 | ENSG00000204460 | 3.66131177483749 | 3.40876502389018 | 3.53503839936384 | LINC01854 |
The ORA method takes a group of significant genes and performs a Fisher's exact test for each term of the selected functional category.
BarplotThe most highly signficant categories in ascending order, according to adjusted p-value. The x-axis represents the number of significant genes found within the functional category.
The most highly signficant categories in descending in categories of gene ratio, defined as the proportion of significant genes that are found in the functional category. The x-axis represents the gene ratio and the dot size the number of genes associated with the functional category.
Distributions of Log2FC
This plot shows the distribution of gene Log2FC that enriched the top enriched functional term/pathways. The X axis repressent the distribution values. The color of the distribution repressents the FDR of the enrichment. The vertical lines represents the first, second and third quartiles.
Gene-Concept Network
The network connects the top functional categories (brown nodes) to their associated genes (grey or colored nodes). The size of the functional category nodes shows the number of connected genes.
The top functional categories (nodes), connected if they share genes. Edge thickness represents the number of shared genes. Nodes size represents the number of significant genes within the category.
Significant genes (x-axis) and the functional categories in which they appear.
Upsetplot
Genes are clustered according to shared enriched categories. The y-axis shows the number of genes belonging to the different clusters (top) and categories to which they belong (bottom).
The ORA method takes a group of significant genes and performs a Fisher's exact test for each term of the selected functional category.
BarplotThe most highly signficant categories in ascending order, according to adjusted p-value. The x-axis represents the number of significant genes found within the functional category.
The most highly signficant categories in descending in categories of gene ratio, defined as the proportion of significant genes that are found in the functional category. The x-axis represents the gene ratio and the dot size the number of genes associated with the functional category.
Distributions of Log2FC
This plot shows the distribution of gene Log2FC that enriched the top enriched functional term/pathways. The X axis repressent the distribution values. The color of the distribution repressents the FDR of the enrichment. The vertical lines represents the first, second and third quartiles.
Gene-Concept Network
The network connects the top functional categories (brown nodes) to their associated genes (grey or colored nodes). The size of the functional category nodes shows the number of connected genes.
The top functional categories (nodes), connected if they share genes. Edge thickness represents the number of shared genes. Nodes size represents the number of significant genes within the category.
Significant genes (x-axis) and the functional categories in which they appear.
Upsetplot
Genes are clustered according to shared enriched categories. The y-axis shows the number of genes belonging to the different clusters (top) and categories to which they belong (bottom).
The ORA method takes a group of significant genes and performs a Fisher's exact test for each term of the selected functional category.
BarplotThe most highly signficant categories in ascending order, according to adjusted p-value. The x-axis represents the number of significant genes found within the functional category.
The most highly signficant categories in descending in categories of gene ratio, defined as the proportion of significant genes that are found in the functional category. The x-axis represents the gene ratio and the dot size the number of genes associated with the functional category.
Distributions of Log2FC
This plot shows the distribution of gene Log2FC that enriched the top enriched functional term/pathways. The X axis repressent the distribution values. The color of the distribution repressents the FDR of the enrichment. The vertical lines represents the first, second and third quartiles.
Gene-Concept Network
The network connects the top functional categories (brown nodes) to their associated genes (grey or colored nodes). The size of the functional category nodes shows the number of connected genes.
The top functional categories (nodes), connected if they share genes. Edge thickness represents the number of shared genes. Nodes size represents the number of significant genes within the category.
Significant genes (x-axis) and the functional categories in which they appear.
Upsetplot
Genes are clustered according to shared enriched categories. The y-axis shows the number of genes belonging to the different clusters (top) and categories to which they belong (bottom).
The ORA method takes a group of significant genes and performs a Fisher's exact test for each term of the selected functional category.
BarplotThe most highly signficant categories in ascending order, according to adjusted p-value. The x-axis represents the number of significant genes found within the functional category.
The most highly signficant categories in descending in categories of gene ratio, defined as the proportion of significant genes that are found in the functional category. The x-axis represents the gene ratio and the dot size the number of genes associated with the functional category.
Distributions of Log2FC
This plot shows the distribution of gene Log2FC that enriched the top enriched functional term/pathways. The X axis repressent the distribution values. The color of the distribution repressents the FDR of the enrichment. The vertical lines represents the first, second and third quartiles.
Gene-Concept Network
The network connects the top functional categories (brown nodes) to their associated genes (grey or colored nodes). The size of the functional category nodes shows the number of connected genes.
The top functional categories (nodes), connected if they share genes. Edge thickness represents the number of shared genes. Nodes size represents the number of significant genes within the category.
Significant genes (x-axis) and the functional categories in which they appear.
Upsetplot
Genes are clustered according to shared enriched categories. The y-axis shows the number of genes belonging to the different clusters (top) and categories to which they belong (bottom).
The ORA method takes a group of significant genes and performs a Fisher's exact test for each term of the selected functional category.
BarplotThe most highly signficant categories in ascending order, according to adjusted p-value. The x-axis represents the number of significant genes found within the functional category.
The most highly signficant categories in descending in categories of gene ratio, defined as the proportion of significant genes that are found in the functional category. The x-axis represents the gene ratio and the dot size the number of genes associated with the functional category.
Distributions of Log2FC
This plot shows the distribution of gene Log2FC that enriched the top enriched functional term/pathways. The X axis repressent the distribution values. The color of the distribution repressents the FDR of the enrichment. The vertical lines represents the first, second and third quartiles.
Gene-Concept Network
The network connects the top functional categories (brown nodes) to their associated genes (grey or colored nodes). The size of the functional category nodes shows the number of connected genes.
The top functional categories (nodes), connected if they share genes. Edge thickness represents the number of shared genes. Nodes size represents the number of significant genes within the category.
Significant genes (x-axis) and the functional categories in which they appear.
Upsetplot
Genes are clustered according to shared enriched categories. The y-axis shows the number of genes belonging to the different clusters (top) and categories to which they belong (bottom).
| GO.ID | Term | positive.PC.1 | negative.PC.1 | positive.PC.2 | negative.PC.2 |
|---|---|---|---|---|---|
| GO:0002181 | cytoplasmic translation | 4.07e-18 | NA | 5.41e-05 | NA |
| GO:0006412 | translation | 8.60e-08 | NA | 1.77e-03 | NA |
| GO:0006119 | oxidative phosphorylation | 9.76e-07 | NA | NA | NA |
| GO:0045333 | cellular respiration | 4.24e-06 | NA | NA | NA |
| GO:0044419 | biological process involved in interspec... | 7.28e-06 | NA | NA | NA |
| GO:0043207 | response to external biotic stimulus | 1.31e-05 | NA | NA | NA |
| GO:0051707 | response to other organism | 1.31e-05 | NA | NA | NA |
| GO:0006955 | immune response | 1.31e-05 | NA | NA | NA |
| GO:1902600 | proton transmembrane transport | 2.93e-05 | NA | NA | NA |
| GO:0009060 | aerobic respiration | 3.20e-05 | NA | NA | NA |
| GO:0009607 | response to biotic stimulus | 3.41e-05 | NA | NA | NA |
| GO:0019538 | protein metabolic process | 3.41e-05 | NA | NA | NA |
| GO:0006508 | proteolysis | 3.98e-05 | NA | NA | NA |
| GO:0006952 | defense response | 4.73e-05 | NA | NA | NA |
| GO:0042773 | ATP synthesis coupled electron transport | 5.64e-05 | NA | NA | NA |
| GO:0042775 | mitochondrial ATP synthesis coupled elec... | 5.64e-05 | NA | NA | NA |
| GO:0022904 | respiratory electron transport chain | 6.86e-05 | NA | NA | NA |
| GO:0002376 | immune system process | 7.79e-05 | NA | NA | NA |
| GO:0002504 | antigen processing and presentation of p... | 9.25e-05 | NA | NA | NA |
| GO:1990748 | cellular detoxification | 1.05e-04 | NA | NA | NA |
| GO:0019882 | antigen processing and presentation | 1.05e-04 | NA | 6.38e-03 | NA |
| GO:0002683 | negative regulation of immune system pro... | 1.31e-04 | NA | NA | NA |
| GO:0048002 | antigen processing and presentation of p... | 1.36e-04 | NA | 1.15e-02 | NA |
| GO:0019646 | aerobic electron transport chain | 1.38e-04 | NA | NA | NA |
| GO:0006959 | humoral immune response | 1.45e-04 | NA | NA | NA |
| GO:0097237 | cellular response to toxic substance | 1.45e-04 | NA | NA | NA |
| GO:0001819 | positive regulation of cytokine producti... | 1.63e-04 | NA | NA | NA |
| GO:0002495 | antigen processing and presentation of p... | 1.63e-04 | NA | 4.75e-02 | NA |
| GO:0009605 | response to external stimulus | 2.14e-04 | NA | NA | NA |
| GO:0051246 | regulation of protein metabolic process | 2.93e-04 | NA | NA | NA |
| GO:0070431 | nucleotide-binding oligomerization domai... | 3.40e-04 | NA | NA | NA |
| GO:0030162 | regulation of proteolysis | 3.40e-04 | NA | NA | NA |
| GO:0002399 | MHC class II protein complex assembly | 3.40e-04 | NA | 6.28e-05 | NA |
| GO:0002503 | peptide antigen assembly with MHC class ... | 3.40e-04 | NA | 6.28e-05 | NA |
| GO:0022900 | electron transport chain | 3.40e-04 | NA | NA | NA |
| GO:0030163 | protein catabolic process | 3.58e-04 | NA | NA | NA |
| GO:0001906 | cell killing | 3.58e-04 | NA | 2.86e-02 | NA |
| GO:0071634 | regulation of transforming growth factor... | 4.14e-04 | NA | NA | NA |
| GO:0002698 | negative regulation of immune effector p... | 4.14e-04 | NA | NA | NA |
| GO:0015980 | energy derivation by oxidation of organi... | 4.14e-04 | NA | NA | NA |
| GO:0043069 | negative regulation of programmed cell d... | 5.04e-04 | NA | NA | NA |
| GO:0007035 | vacuolar acidification | 9.04e-04 | NA | NA | NA |
| GO:0051603 | proteolysis involved in protein cataboli... | 9.04e-04 | NA | NA | NA |
| GO:0098754 | detoxification | 9.04e-04 | NA | NA | NA |
| GO:0051452 | intracellular pH reduction | 9.09e-04 | NA | NA | NA |
| GO:0140546 | defense response to symbiont | 9.09e-04 | NA | NA | NA |
| GO:0001817 | regulation of cytokine production | 9.09e-04 | NA | NA | NA |
| GO:0098542 | defense response to other organism | 9.09e-04 | NA | NA | NA |
| GO:0110076 | negative regulation of ferroptosis | 9.09e-04 | NA | NA | NA |
| GO:0098869 | cellular oxidant detoxification | 9.74e-04 | NA | NA | NA |
| GO:0043066 | negative regulation of apoptotic process | 1.05e-03 | NA | NA | NA |
| GO:0002437 | inflammatory response to antigenic stimu... | 1.10e-03 | NA | NA | NA |
| GO:0019730 | antimicrobial humoral response | 1.10e-03 | NA | 1.89e-02 | NA |
| GO:0061844 | antimicrobial humoral immune response me... | 1.10e-03 | NA | 7.20e-03 | NA |
| GO:0045087 | innate immune response | 1.10e-03 | NA | NA | NA |
| GO:0001816 | cytokine production | 1.14e-03 | NA | NA | NA |
| GO:0090026 | positive regulation of monocyte chemotax... | 1.32e-03 | NA | NA | NA |
| GO:0032543 | mitochondrial translation | 1.36e-03 | NA | NA | NA |
| GO:0030003 | intracellular monoatomic cation homeosta... | 1.73e-03 | NA | NA | NA |
| GO:0002710 | negative regulation of T cell mediated i... | 1.81e-03 | NA | NA | NA |
| GO:0002682 | regulation of immune system process | 1.81e-03 | NA | NA | NA |
| GO:0019886 | antigen processing and presentation of e... | 1.81e-03 | NA | 3.02e-02 | NA |
| GO:1902956 | regulation of mitochondrial electron tra... | 1.87e-03 | NA | NA | NA |
| GO:0002478 | antigen processing and presentation of e... | 1.89e-03 | NA | 1.72e-02 | NA |
| GO:0030641 | regulation of cellular pH | 1.92e-03 | NA | NA | NA |
| GO:0002548 | monocyte chemotaxis | 2.44e-03 | NA | NA | NA |
| GO:0050868 | negative regulation of T cell activation | 2.67e-03 | NA | NA | NA |
| GO:0006885 | regulation of pH | 2.94e-03 | NA | NA | NA |
| GO:0051049 | regulation of transport | 2.97e-03 | NA | NA | NA |
| GO:0006873 | intracellular monoatomic ion homeostasis | 3.22e-03 | NA | NA | NA |
| GO:0050777 | negative regulation of immune response | 3.22e-03 | NA | NA | NA |
| GO:1905446 | regulation of mitochondrial ATP synthesi... | 3.44e-03 | NA | NA | NA |
| GO:0097401 | synaptic vesicle lumen acidification | 3.45e-03 | NA | NA | NA |
| GO:0009617 | response to bacterium | 3.46e-03 | NA | NA | NA |
| GO:0051453 | regulation of intracellular pH | 3.46e-03 | NA | NA | NA |
| GO:0051050 | positive regulation of transport | 3.60e-03 | NA | NA | NA |
| GO:0050817 | coagulation | 3.68e-03 | NA | NA | NA |
| GO:0050776 | regulation of immune response | 3.78e-03 | NA | NA | NA |
| GO:0097529 | myeloid leukocyte migration | 3.99e-03 | NA | NA | NA |
| GO:0050866 | negative regulation of cell activation | 4.36e-03 | NA | NA | NA |
| GO:0002237 | response to molecule of bacterial origin | 4.70e-03 | NA | NA | NA |
| GO:0006954 | inflammatory response | 4.70e-03 | NA | NA | NA |
| GO:0002687 | positive regulation of leukocyte migrati... | 4.71e-03 | NA | NA | NA |
| GO:0019884 | antigen processing and presentation of e... | 4.72e-03 | NA | 3.51e-03 | NA |
| GO:0032496 | response to lipopolysaccharide | 4.78e-03 | NA | NA | NA |
| GO:0002697 | regulation of immune effector process | 4.78e-03 | NA | NA | NA |
| GO:0097250 | mitochondrial respirasome assembly | 4.78e-03 | NA | NA | NA |
| GO:0002250 | adaptive immune response | 4.89e-03 | NA | NA | NA |
| GO:0042592 | homeostatic process | 4.99e-03 | NA | NA | NA |
| GO:0042110 | T cell activation | 5.05e-03 | NA | NA | NA |
| GO:0009057 | macromolecule catabolic process | 5.05e-03 | NA | NA | NA |
| GO:0015986 | proton motive force-driven ATP synthesis | 5.05e-03 | NA | NA | NA |
| GO:0006879 | intracellular iron ion homeostasis | 5.10e-03 | NA | NA | NA |
| GO:0032613 | interleukin-10 production | 5.10e-03 | NA | NA | NA |
| GO:0032653 | regulation of interleukin-10 production | 5.10e-03 | NA | NA | NA |
| GO:0007596 | blood coagulation | 6.67e-03 | NA | NA | NA |
| GO:1904063 | negative regulation of cation transmembr... | 6.69e-03 | NA | NA | NA |
| GO:0016188 | synaptic vesicle maturation | 6.86e-03 | NA | NA | NA |
| GO:0009636 | response to toxic substance | 6.86e-03 | NA | NA | NA |
| GO:0002252 | immune effector process | 7.04e-03 | NA | NA | NA |
| GO:0030309 | poly-N-acetyllactosamine metabolic proce... | 7.11e-03 | NA | NA | NA |
| GO:0030311 | poly-N-acetyllactosamine biosynthetic pr... | 7.11e-03 | NA | NA | NA |
| GO:0032101 | regulation of response to external stimu... | 7.11e-03 | NA | NA | NA |
| GO:1903707 | negative regulation of hemopoiesis | 7.15e-03 | NA | NA | NA |
| GO:0010628 | positive regulation of gene expression | 7.22e-03 | NA | NA | NA |
| GO:0001775 | cell activation | 7.34e-03 | NA | NA | NA |
| GO:0002396 | MHC protein complex assembly | 7.39e-03 | NA | 1.34e-03 | NA |
| GO:0002501 | peptide antigen assembly with MHC protei... | 7.39e-03 | NA | 1.34e-03 | NA |
| GO:1901652 | response to peptide | 7.43e-03 | NA | NA | NA |
| GO:0006754 | ATP biosynthetic process | 7.43e-03 | NA | NA | NA |
| GO:1901135 | carbohydrate derivative metabolic proces... | 7.51e-03 | NA | NA | NA |
| GO:0036296 | response to increased oxygen levels | 7.53e-03 | NA | NA | NA |
| GO:0002695 | negative regulation of leukocyte activat... | 7.53e-03 | NA | NA | NA |
| GO:0042776 | proton motive force-driven mitochondrial... | 7.88e-03 | NA | NA | NA |
| GO:0006091 | generation of precursor metabolites and ... | 7.88e-03 | NA | NA | NA |
| GO:0002709 | regulation of T cell mediated immunity | 8.46e-03 | NA | NA | NA |
| GO:0002685 | regulation of leukocyte migration | 8.46e-03 | NA | NA | NA |
| GO:0031347 | regulation of defense response | 8.46e-03 | NA | NA | NA |
| GO:0006121 | mitochondrial electron transport, succin... | 8.46e-03 | NA | NA | NA |
| GO:0016050 | vesicle organization | 8.73e-03 | NA | NA | NA |
| GO:0090025 | regulation of monocyte chemotaxis | 9.08e-03 | NA | NA | NA |
| GO:0034097 | response to cytokine | 9.10e-03 | NA | NA | NA |
| GO:0034109 | homotypic cell-cell adhesion | 9.14e-03 | NA | NA | NA |
| GO:0002690 | positive regulation of leukocyte chemota... | 9.22e-03 | NA | NA | NA |
| GO:0007042 | lysosomal lumen acidification | 9.26e-03 | NA | NA | NA |
| GO:0055080 | monoatomic cation homeostasis | 9.32e-03 | NA | NA | NA |
| GO:0035751 | regulation of lysosomal lumen pH | 9.34e-03 | NA | NA | NA |
| GO:0031987 | locomotion involved in locomotory behavi... | 9.34e-03 | NA | NA | NA |
| GO:2000767 | positive regulation of cytoplasmic trans... | 9.37e-03 | NA | NA | NA |
| GO:0050801 | monoatomic ion homeostasis | 9.43e-03 | NA | NA | NA |
| GO:0050900 | leukocyte migration | 9.79e-03 | NA | NA | NA |
| GO:0007599 | hemostasis | 1.01e-02 | NA | NA | NA |
| GO:0034374 | low-density lipoprotein particle remodel... | 1.03e-02 | NA | NA | NA |
| GO:0006812 | monoatomic cation transport | 1.04e-02 | NA | NA | NA |
| GO:0055082 | intracellular chemical homeostasis | 1.06e-02 | NA | NA | NA |
| GO:0009611 | response to wounding | 1.11e-02 | NA | NA | NA |
| GO:0002684 | positive regulation of immune system pro... | 1.16e-02 | NA | NA | NA |
| GO:1902253 | regulation of intrinsic apoptotic signal... | 1.16e-02 | NA | NA | NA |
| GO:0002424 | T cell mediated immune response to tumor... | 1.16e-02 | NA | NA | NA |
| GO:0051250 | negative regulation of lymphocyte activa... | 1.19e-02 | NA | NA | NA |
| GO:0045861 | negative regulation of proteolysis | 1.19e-02 | NA | NA | NA |
| GO:0048524 | positive regulation of viral process | 1.19e-02 | NA | NA | NA |
| GO:0033108 | mitochondrial respiratory chain complex ... | 1.19e-02 | NA | NA | NA |
| GO:0048584 | positive regulation of response to stimu... | 1.23e-02 | NA | NA | NA |
| GO:0043457 | regulation of cellular respiration | 1.24e-02 | NA | NA | NA |
| GO:0042060 | wound healing | 1.24e-02 | NA | NA | NA |
| GO:0002861 | regulation of inflammatory response to a... | 1.24e-02 | NA | NA | NA |
| GO:0061077 | chaperone-mediated protein folding | 1.24e-02 | NA | NA | NA |
| GO:0048227 | plasma membrane to endosome transport | 1.31e-02 | NA | NA | NA |
| GO:1902106 | negative regulation of leukocyte differe... | 1.35e-02 | NA | NA | NA |
| GO:0002831 | regulation of response to biotic stimulu... | 1.35e-02 | NA | NA | NA |
| GO:0051248 | negative regulation of protein metabolic... | 1.35e-02 | NA | NA | NA |
| GO:0002536 | respiratory burst involved in inflammato... | 1.36e-02 | NA | NA | NA |
| GO:0038159 | C-X-C chemokine receptor CXCR4 signaling... | 1.41e-02 | NA | NA | NA |
| GO:0023056 | positive regulation of signaling | 1.43e-02 | NA | NA | NA |
| GO:0019941 | modification-dependent protein catabolic... | 1.43e-02 | NA | NA | NA |
| GO:0019725 | cellular homeostasis | 1.44e-02 | NA | NA | NA |
| GO:0032103 | positive regulation of response to exter... | 1.45e-02 | NA | NA | NA |
| GO:0006123 | mitochondrial electron transport, cytoch... | 1.45e-02 | NA | NA | NA |
| GO:0006511 | ubiquitin-dependent protein catabolic pr... | 1.50e-02 | NA | NA | NA |
| GO:0032609 | type II interferon production | 1.53e-02 | NA | NA | NA |
| GO:0032649 | regulation of type II interferon product... | 1.53e-02 | NA | NA | NA |
| GO:1903038 | negative regulation of leukocyte cell-ce... | 1.56e-02 | NA | NA | NA |
| GO:0002438 | acute inflammatory response to antigenic... | 1.56e-02 | NA | NA | NA |
| GO:1902622 | regulation of neutrophil migration | 1.65e-02 | NA | NA | NA |
| GO:0032757 | positive regulation of interleukin-8 pro... | 1.67e-02 | NA | NA | NA |
| GO:0010647 | positive regulation of cell communicatio... | 1.68e-02 | NA | NA | NA |
| GO:0070244 | negative regulation of thymocyte apoptot... | 1.69e-02 | NA | NA | NA |
| GO:0071604 | transforming growth factor beta producti... | 1.70e-02 | NA | NA | NA |
| GO:0051604 | protein maturation | 1.75e-02 | NA | NA | NA |
| GO:0052547 | regulation of peptidase activity | 1.82e-02 | NA | NA | NA |
| GO:0032733 | positive regulation of interleukin-10 pr... | 1.82e-02 | NA | NA | NA |
| GO:0006413 | translational initiation | 1.82e-02 | NA | 3.57e-02 | NA |
| GO:0140053 | mitochondrial gene expression | 1.86e-02 | NA | NA | NA |
| GO:0051051 | negative regulation of transport | 1.92e-02 | NA | NA | NA |
| GO:1902624 | positive regulation of neutrophil migrat... | 1.98e-02 | NA | NA | NA |
| GO:0009145 | purine nucleoside triphosphate biosynthe... | 2.05e-02 | NA | NA | NA |
| GO:0098662 | inorganic cation transmembrane transport | 2.05e-02 | NA | NA | NA |
| GO:0070527 | platelet aggregation | 2.05e-02 | NA | NA | NA |
| GO:0070432 | regulation of nucleotide-binding oligome... | 2.05e-02 | NA | NA | NA |
| GO:0010498 | proteasomal protein catabolic process | 2.05e-02 | NA | NA | NA |
| GO:0007159 | leukocyte cell-cell adhesion | 2.05e-02 | NA | NA | NA |
| GO:0002286 | T cell activation involved in immune res... | 2.14e-02 | NA | NA | NA |
| GO:0045321 | leukocyte activation | 2.17e-02 | NA | NA | NA |
| GO:0032689 | negative regulation of type II interfero... | 2.17e-02 | NA | NA | NA |
| GO:0019883 | antigen processing and presentation of e... | 2.17e-02 | NA | 7.05e-03 | NA |
| GO:0071345 | cellular response to cytokine stimulus | 2.23e-02 | NA | NA | NA |
| GO:0002688 | regulation of leukocyte chemotaxis | 2.23e-02 | NA | NA | NA |
| GO:0032944 | regulation of mononuclear cell prolifera... | 2.26e-02 | NA | NA | NA |
| GO:0042274 | ribosomal small subunit biogenesis | 2.26e-02 | NA | NA | NA |
| GO:0007220 | Notch receptor processing | 2.28e-02 | NA | NA | NA |
| GO:0002707 | negative regulation of lymphocyte mediat... | 2.28e-02 | NA | NA | NA |
| GO:0001909 | leukocyte mediated cytotoxicity | 2.28e-02 | NA | NA | NA |
| GO:0022408 | negative regulation of cell-cell adhesio... | 2.28e-02 | NA | NA | NA |
| GO:0034766 | negative regulation of monoatomic ion tr... | 2.28e-02 | NA | NA | NA |
| GO:0043632 | modification-dependent macromolecule cat... | 2.29e-02 | NA | NA | NA |
| GO:0002862 | negative regulation of inflammatory resp... | 2.31e-02 | NA | NA | NA |
| GO:0009206 | purine ribonucleoside triphosphate biosy... | 2.31e-02 | NA | NA | NA |
| GO:0031348 | negative regulation of defense response | 2.32e-02 | NA | NA | NA |
| GO:0050670 | regulation of lymphocyte proliferation | 2.33e-02 | NA | NA | NA |
| GO:0043067 | regulation of programmed cell death | 2.34e-02 | NA | NA | NA |
| GO:0002840 | regulation of T cell mediated immune res... | 2.36e-02 | NA | NA | NA |
| GO:0042129 | regulation of T cell proliferation | 2.37e-02 | NA | NA | NA |
| GO:0042127 | regulation of cell population proliferat... | 2.37e-02 | NA | NA | NA |
| GO:0002456 | T cell mediated immunity | 2.40e-02 | NA | NA | NA |
| GO:0002367 | cytokine production involved in immune r... | 2.44e-02 | NA | NA | NA |
| GO:0002718 | regulation of cytokine production involv... | 2.44e-02 | NA | NA | NA |
| GO:0002443 | leukocyte mediated immunity | 2.46e-02 | NA | NA | NA |
| GO:0042221 | response to chemical | 2.47e-02 | NA | NA | NA |
| GO:2001258 | negative regulation of cation channel ac... | 2.55e-02 | NA | NA | NA |
| GO:0046649 | lymphocyte activation | 2.55e-02 | NA | NA | NA |
| GO:2001234 | negative regulation of apoptotic signali... | 2.55e-02 | NA | NA | NA |
| GO:0006956 | complement activation | 2.57e-02 | NA | NA | NA |
| GO:0071706 | tumor necrosis factor superfamily cytoki... | 2.60e-02 | NA | NA | NA |
| GO:1903555 | regulation of tumor necrosis factor supe... | 2.60e-02 | NA | NA | NA |
| GO:0032879 | regulation of localization | 2.60e-02 | NA | NA | NA |
| GO:0050778 | positive regulation of immune response | 2.60e-02 | NA | NA | NA |
| GO:0071492 | cellular response to UV-A | 2.60e-02 | NA | NA | NA |
| GO:0002704 | negative regulation of leukocyte mediate... | 2.65e-02 | NA | NA | NA |
| GO:0009056 | catabolic process | 2.65e-02 | NA | NA | NA |
| GO:0001913 | T cell mediated cytotoxicity | 2.70e-02 | NA | NA | NA |
| GO:0048878 | chemical homeostasis | 2.73e-02 | NA | NA | NA |
| GO:0070663 | regulation of leukocyte proliferation | 2.73e-02 | NA | NA | NA |
| GO:0065008 | regulation of biological quality | 2.73e-02 | NA | NA | NA |
| GO:0071878 | negative regulation of adenylate cyclase... | 2.82e-02 | NA | NA | NA |
| GO:0007162 | negative regulation of cell adhesion | 2.83e-02 | NA | NA | NA |
| GO:0050765 | negative regulation of phagocytosis | 2.88e-02 | NA | NA | NA |
| GO:0006465 | signal peptide processing | 2.88e-02 | NA | NA | NA |
| GO:0009967 | positive regulation of signal transducti... | 2.88e-02 | NA | NA | NA |
| GO:0061450 | trophoblast cell migration | 2.93e-02 | NA | NA | NA |
| GO:1901163 | regulation of trophoblast cell migration | 2.93e-02 | NA | NA | NA |
| GO:0042744 | hydrogen peroxide catabolic process | 2.95e-02 | NA | NA | NA |
| GO:0060231 | mesenchymal to epithelial transition | 2.99e-02 | NA | NA | NA |
| GO:0006968 | cellular defense response | 2.99e-02 | NA | NA | NA |
| GO:0015734 | taurine transmembrane transport | 2.99e-02 | NA | NA | NA |
| GO:0042918 | alkanesulfonate transmembrane transport | 2.99e-02 | NA | NA | NA |
| GO:0034762 | regulation of transmembrane transport | 2.99e-02 | NA | NA | NA |
| GO:0008284 | positive regulation of cell population p... | 3.00e-02 | NA | NA | NA |
| GO:2001242 | regulation of intrinsic apoptotic signal... | 3.11e-02 | NA | 3.47e-02 | NA |
| GO:0097212 | lysosomal membrane organization | 3.16e-02 | NA | NA | NA |
| GO:0007005 | mitochondrion organization | 3.16e-02 | NA | NA | NA |
| GO:0038061 | non-canonical NF-kappaB signal transduct... | 3.18e-02 | NA | NA | NA |
| GO:0018958 | phenol-containing compound metabolic pro... | 3.24e-02 | NA | NA | NA |
| GO:0032943 | mononuclear cell proliferation | 3.24e-02 | NA | NA | NA |
| GO:0060479 | lung cell differentiation | 3.24e-02 | NA | NA | NA |
| GO:0060487 | lung epithelial cell differentiation | 3.24e-02 | NA | NA | NA |
| GO:0031647 | regulation of protein stability | 3.25e-02 | NA | NA | NA |
| GO:0050727 | regulation of inflammatory response | 3.25e-02 | NA | NA | NA |
| GO:1903320 | regulation of protein modification by sm... | 3.30e-02 | NA | NA | NA |
| GO:0060054 | positive regulation of epithelial cell p... | 3.36e-02 | NA | NA | NA |
| GO:0071636 | positive regulation of transforming grow... | 3.43e-02 | NA | NA | NA |
| GO:0007040 | lysosome organization | 3.51e-02 | NA | NA | NA |
| GO:0080171 | lytic vacuole organization | 3.51e-02 | NA | NA | NA |
| GO:0042981 | regulation of apoptotic process | 3.57e-02 | NA | NA | NA |
| GO:0098609 | cell-cell adhesion | 3.57e-02 | NA | 4.52e-02 | NA |
| GO:0007032 | endosome organization | 3.67e-02 | NA | NA | NA |
| GO:0031638 | zymogen activation | 3.67e-02 | NA | NA | NA |
| GO:0032640 | tumor necrosis factor production | 3.88e-02 | NA | NA | NA |
| GO:0032680 | regulation of tumor necrosis factor prod... | 3.88e-02 | NA | NA | NA |
| GO:0006958 | complement activation, classical pathway | 3.94e-02 | NA | NA | NA |
| GO:0046651 | lymphocyte proliferation | 4.07e-02 | NA | NA | NA |
| GO:2001233 | regulation of apoptotic signaling pathwa... | 4.09e-02 | NA | NA | NA |
| GO:0002449 | lymphocyte mediated immunity | 4.12e-02 | NA | NA | NA |
| GO:0043161 | proteasome-mediated ubiquitin-dependent ... | 4.12e-02 | NA | NA | NA |
| GO:1903037 | regulation of leukocyte cell-cell adhesi... | 4.12e-02 | NA | NA | NA |
| GO:1903911 | positive regulation of receptor clusteri... | 4.13e-02 | NA | NA | NA |
| GO:0003015 | heart process | 4.13e-02 | NA | NA | NA |
| GO:0019076 | viral release from host cell | 4.13e-02 | NA | NA | NA |
| GO:0035891 | exit from host cell | 4.13e-02 | NA | NA | NA |
| GO:0098655 | monoatomic cation transmembrane transpor... | 4.13e-02 | NA | NA | NA |
| GO:0006120 | mitochondrial electron transport, NADH t... | 4.14e-02 | NA | NA | NA |
| GO:2001257 | regulation of cation channel activity | 4.16e-02 | NA | NA | NA |
| GO:1903170 | negative regulation of calcium ion trans... | 4.18e-02 | NA | NA | NA |
| GO:1903715 | regulation of aerobic respiration | 4.20e-02 | NA | NA | NA |
| GO:0032906 | transforming growth factor beta2 product... | 4.20e-02 | NA | NA | NA |
| GO:0032909 | regulation of transforming growth factor... | 4.20e-02 | NA | NA | NA |
| GO:0016485 | protein processing | 4.20e-02 | NA | NA | NA |
| GO:0045088 | regulation of innate immune response | 4.26e-02 | NA | NA | NA |
| GO:0031341 | regulation of cell killing | 4.30e-02 | NA | NA | NA |
| GO:0042373 | vitamin K metabolic process | 4.33e-02 | NA | NA | NA |
| GO:0031349 | positive regulation of defense response | 4.33e-02 | NA | NA | NA |
| GO:0070434 | positive regulation of nucleotide-bindin... | 4.33e-02 | NA | NA | NA |
| GO:0050865 | regulation of cell activation | 4.37e-02 | NA | NA | NA |
| GO:0090022 | regulation of neutrophil chemotaxis | 4.39e-02 | NA | NA | NA |
| GO:1901857 | positive regulation of cellular respirat... | 4.49e-02 | NA | NA | NA |
| GO:1900044 | regulation of protein K63-linked ubiquit... | 4.49e-02 | NA | NA | NA |
| GO:0016032 | viral process | 4.57e-02 | NA | NA | NA |
| GO:0052548 | regulation of endopeptidase activity | 4.58e-02 | NA | NA | NA |
| GO:0044403 | biological process involved in symbiotic... | 4.65e-02 | NA | NA | NA |
| GO:0036295 | cellular response to increased oxygen le... | 4.65e-02 | NA | NA | NA |
| GO:0031640 | killing of cells of another organism | 4.65e-02 | NA | 6.64e-03 | NA |
| GO:0141061 | disruption of cell in another organism | 4.65e-02 | NA | 6.64e-03 | NA |
| GO:1901873 | regulation of post-translational protein... | 4.66e-02 | NA | NA | NA |
| GO:2001188 | regulation of T cell activation via T ce... | 4.66e-02 | NA | NA | NA |
| GO:0050863 | regulation of T cell activation | 4.80e-02 | NA | 3.57e-02 | NA |
| GO:0002460 | adaptive immune response based on somati... | 4.80e-02 | NA | NA | NA |
| GO:0006325 | chromatin organization | NA | 1.08e-12 | 2.90e-06 | NA |
| GO:0006338 | chromatin remodeling | NA | 3.29e-11 | 1.28e-07 | NA |
| GO:0006261 | DNA-templated DNA replication | NA | 5.97e-10 | 4.03e-04 | NA |
| GO:0006281 | DNA repair | NA | 8.65e-09 | 1.87e-03 | NA |
| GO:0006974 | DNA damage response | NA | 1.66e-08 | 3.90e-03 | NA |
| GO:0090304 | nucleic acid metabolic process | NA | 3.76e-08 | 1.87e-02 | NA |
| GO:0006260 | DNA replication | NA | 9.19e-08 | 1.01e-05 | NA |
| GO:0006259 | DNA metabolic process | NA | 3.97e-07 | 3.04e-04 | NA |
| GO:0006139 | nucleobase-containing compound metabolic... | NA | 3.97e-07 | NA | NA |
| GO:0006302 | double-strand break repair | NA | 6.59e-07 | 9.66e-05 | NA |
| GO:0022402 | cell cycle process | NA | 9.61e-07 | 1.12e-11 | NA |
| GO:0007049 | cell cycle | NA | 4.34e-06 | 1.12e-11 | NA |
| GO:0010564 | regulation of cell cycle process | NA | 6.53e-06 | 1.53e-10 | NA |
| GO:0019219 | regulation of nucleobase-containing comp... | NA | 2.00e-05 | NA | NA |
| GO:0098534 | centriole assembly | NA | 1.50e-04 | NA | NA |
| GO:0033260 | nuclear DNA replication | NA | 2.40e-04 | NA | NA |
| GO:0051276 | chromosome organization | NA | 2.55e-04 | 8.29e-14 | NA |
| GO:0016043 | cellular component organization | NA | 2.55e-04 | 3.16e-03 | NA |
| GO:0007010 | cytoskeleton organization | NA | 3.31e-04 | NA | NA |
| GO:2001141 | regulation of RNA biosynthetic process | NA | 3.31e-04 | NA | NA |
| GO:0006355 | regulation of DNA-templated transcriptio... | NA | 3.31e-04 | NA | NA |
| GO:0051726 | regulation of cell cycle | NA | 3.97e-04 | 1.60e-10 | NA |
| GO:0051056 | regulation of small GTPase mediated sign... | NA | 3.97e-04 | NA | NA |
| GO:0051252 | regulation of RNA metabolic process | NA | 5.11e-04 | NA | NA |
| GO:0045005 | DNA-templated DNA replication maintenanc... | NA | 5.17e-04 | 2.87e-02 | NA |
| GO:0044786 | cell cycle DNA replication | NA | 6.13e-04 | 2.93e-02 | NA |
| GO:0007099 | centriole replication | NA | 6.60e-04 | NA | NA |
| GO:0006351 | DNA-templated transcription | NA | 6.84e-04 | NA | NA |
| GO:0141187 | nucleic acid biosynthetic process | NA | 8.04e-04 | NA | NA |
| GO:0000727 | double-strand break repair via break-ind... | NA | 8.91e-04 | NA | NA |
| GO:0045935 | positive regulation of nucleobase-contai... | NA | 8.91e-04 | 4.75e-02 | NA |
| GO:0006366 | transcription by RNA polymerase II | NA | 8.91e-04 | NA | NA |
| GO:0000278 | mitotic cell cycle | NA | 1.05e-03 | 2.32e-12 | NA |
| GO:0016070 | RNA metabolic process | NA | 1.05e-03 | NA | NA |
| GO:0006269 | DNA replication, synthesis of primer | NA | 1.05e-03 | NA | NA |
| GO:0006357 | regulation of transcription by RNA polym... | NA | 1.33e-03 | NA | NA |
| GO:0051052 | regulation of DNA metabolic process | NA | 1.37e-03 | 1.04e-04 | NA |
| GO:0034654 | nucleobase-containing compound biosynthe... | NA | 1.55e-03 | NA | NA |
| GO:0051298 | centrosome duplication | NA | 1.90e-03 | NA | NA |
| GO:0071840 | cellular component organization or bioge... | NA | 2.21e-03 | 3.60e-04 | NA |
| GO:1903047 | mitotic cell cycle process | NA | 2.25e-03 | 1.12e-11 | NA |
| GO:0090329 | regulation of DNA-templated DNA replicat... | NA | 2.30e-03 | NA | NA |
| GO:0032774 | RNA biosynthetic process | NA | 2.70e-03 | NA | NA |
| GO:0007098 | centrosome cycle | NA | 2.84e-03 | NA | NA |
| GO:0000226 | microtubule cytoskeleton organization | NA | 2.84e-03 | 1.26e-04 | NA |
| GO:0031023 | microtubule organizing center organizati... | NA | 2.84e-03 | NA | NA |
| GO:0000724 | double-strand break repair via homologou... | NA | 2.84e-03 | 2.07e-02 | NA |
| GO:0000725 | recombinational repair | NA | 2.84e-03 | 1.61e-02 | NA |
| GO:0034983 | peptidyl-lysine deacetylation | NA | 2.84e-03 | NA | NA |
| GO:1901987 | regulation of cell cycle phase transitio... | NA | 3.16e-03 | 2.99e-07 | NA |
| GO:0000076 | DNA replication checkpoint signaling | NA | 3.65e-03 | NA | NA |
| GO:0018126 | protein hydroxylation | NA | 5.25e-03 | NA | NA |
| GO:0006282 | regulation of DNA repair | NA | 5.25e-03 | 6.03e-03 | NA |
| GO:0007017 | microtubule-based process | NA | 5.25e-03 | 9.83e-04 | NA |
| GO:0051254 | positive regulation of RNA metabolic pro... | NA | 5.63e-03 | NA | NA |
| GO:0006270 | DNA replication initiation | NA | 5.73e-03 | NA | NA |
| GO:0045786 | negative regulation of cell cycle | NA | 7.77e-03 | 2.81e-06 | NA |
| GO:0031297 | replication fork processing | NA | 8.33e-03 | 4.66e-02 | NA |
| GO:0051054 | positive regulation of DNA metabolic pro... | NA | 8.78e-03 | 3.91e-03 | NA |
| GO:1900262 | regulation of DNA-directed DNA polymeras... | NA | 9.38e-03 | NA | NA |
| GO:1900264 | positive regulation of DNA-directed DNA ... | NA | 9.38e-03 | NA | NA |
| GO:0032886 | regulation of microtubule-based process | NA | 1.08e-02 | NA | NA |
| GO:0006996 | organelle organization | NA | 1.23e-02 | 3.01e-02 | NA |
| GO:0036297 | interstrand cross-link repair | NA | 1.30e-02 | NA | NA |
| GO:0030174 | regulation of DNA-templated DNA replicat... | NA | 1.31e-02 | NA | NA |
| GO:0045893 | positive regulation of DNA-templated tra... | NA | 1.34e-02 | NA | NA |
| GO:1902680 | positive regulation of RNA biosynthetic ... | NA | 1.45e-02 | NA | NA |
| GO:2000779 | regulation of double-strand break repair | NA | 1.46e-02 | 3.27e-04 | NA |
| GO:0044782 | cilium organization | NA | 1.61e-02 | NA | NA |
| GO:0010948 | negative regulation of cell cycle proces... | NA | 1.62e-02 | 4.08e-06 | NA |
| GO:0006310 | DNA recombination | NA | 1.69e-02 | 4.82e-03 | NA |
| GO:0032259 | methylation | NA | 1.81e-02 | NA | NA |
| GO:0051984 | positive regulation of chromosome segreg... | NA | 2.40e-02 | 1.22e-03 | NA |
| GO:0000075 | cell cycle checkpoint signaling | NA | 2.94e-02 | 4.29e-04 | NA |
| GO:0040029 | epigenetic regulation of gene expression | NA | 2.94e-02 | 2.45e-03 | NA |
| GO:0006013 | mannose metabolic process | NA | 3.28e-02 | NA | NA |
| GO:0060271 | cilium assembly | NA | 3.61e-02 | NA | NA |
| GO:0033043 | regulation of organelle organization | NA | 3.61e-02 | 1.31e-02 | NA |
| GO:0046985 | positive regulation of hemoglobin biosyn... | NA | 3.61e-02 | NA | NA |
| GO:0006312 | mitotic recombination | NA | 3.76e-02 | NA | NA |
| GO:0009190 | cyclic nucleotide biosynthetic process | NA | 3.79e-02 | NA | NA |
| GO:0044770 | cell cycle phase transition | NA | 3.81e-02 | 1.60e-06 | NA |
| GO:1901990 | regulation of mitotic cell cycle phase t... | NA | 4.10e-02 | 5.50e-07 | NA |
| GO:0046777 | protein autophosphorylation | NA | 4.10e-02 | NA | NA |
| GO:1902017 | regulation of cilium assembly | NA | 4.65e-02 | NA | NA |
| GO:1903251 | multi-ciliated epithelial cell different... | NA | 4.67e-02 | NA | NA |
| GO:1901988 | negative regulation of cell cycle phase ... | NA | 4.87e-02 | 2.30e-05 | NA |
| GO:0007059 | chromosome segregation | NA | NA | 1.05e-12 | NA |
| GO:0000819 | sister chromatid segregation | NA | NA | 1.12e-11 | NA |
| GO:0000280 | nuclear division | NA | NA | 1.12e-11 | NA |
| GO:0034728 | nucleosome organization | NA | NA | 1.89e-11 | NA |
| GO:0098813 | nuclear chromosome segregation | NA | NA | 2.16e-11 | NA |
| GO:0006334 | nucleosome assembly | NA | NA | 1.46e-10 | NA |
| GO:0071824 | protein-DNA complex organization | NA | NA | 1.53e-10 | NA |
| GO:0140014 | mitotic nuclear division | NA | NA | 2.05e-10 | NA |
| GO:0000070 | mitotic sister chromatid segregation | NA | NA | 4.24e-10 | NA |
| GO:0065004 | protein-DNA complex assembly | NA | NA | 1.84e-09 | NA |
| GO:0048285 | organelle fission | NA | NA | 2.00e-09 | NA |
| GO:0007346 | regulation of mitotic cell cycle | NA | NA | 9.90e-09 | NA |
| GO:0051301 | cell division | NA | NA | 2.09e-08 | NA |
| GO:0051983 | regulation of chromosome segregation | NA | NA | 2.53e-08 | NA |
| GO:0033045 | regulation of sister chromatid segregati... | NA | NA | 6.11e-07 | NA |
| GO:1902099 | regulation of metaphase/anaphase transit... | NA | NA | 1.43e-06 | NA |
| GO:0030071 | regulation of mitotic metaphase/anaphase... | NA | NA | 1.86e-06 | NA |
| GO:0033047 | regulation of mitotic sister chromatid s... | NA | NA | 2.24e-06 | NA |
| GO:0090068 | positive regulation of cell cycle proces... | NA | NA | 2.76e-06 | NA |
| GO:0044784 | metaphase/anaphase transition of cell cy... | NA | NA | 3.07e-06 | NA |
| GO:0044772 | mitotic cell cycle phase transition | NA | NA | 3.97e-06 | NA |
| GO:0007091 | metaphase/anaphase transition of mitotic... | NA | NA | 3.97e-06 | NA |
| GO:0045839 | negative regulation of mitotic nuclear d... | NA | NA | 4.24e-06 | NA |
| GO:0051985 | negative regulation of chromosome segreg... | NA | NA | 6.09e-06 | NA |
| GO:0140694 | non-membrane-bounded organelle assembly | NA | NA | 1.01e-05 | NA |
| GO:1902100 | negative regulation of metaphase/anaphas... | NA | NA | 1.15e-05 | NA |
| GO:1905819 | negative regulation of chromosome separa... | NA | NA | 1.15e-05 | NA |
| GO:0033046 | negative regulation of sister chromatid ... | NA | NA | 1.59e-05 | NA |
| GO:0033048 | negative regulation of mitotic sister ch... | NA | NA | 1.59e-05 | NA |
| GO:0045841 | negative regulation of mitotic metaphase... | NA | NA | 1.59e-05 | NA |
| GO:2000816 | negative regulation of mitotic sister ch... | NA | NA | 1.59e-05 | NA |
| GO:1905818 | regulation of chromosome separation | NA | NA | 1.81e-05 | NA |
| GO:0033044 | regulation of chromosome organization | NA | NA | 2.25e-05 | NA |
| GO:0051304 | chromosome separation | NA | NA | 2.47e-05 | NA |
| GO:0007088 | regulation of mitotic nuclear division | NA | NA | 3.36e-05 | NA |
| GO:0031577 | spindle checkpoint signaling | NA | NA | 3.88e-05 | NA |
| GO:0007052 | mitotic spindle organization | NA | NA | 4.77e-05 | NA |
| GO:0045930 | negative regulation of mitotic cell cycl... | NA | NA | 4.85e-05 | NA |
| GO:0007094 | mitotic spindle assembly checkpoint sign... | NA | NA | 5.31e-05 | NA |
| GO:0071173 | spindle assembly checkpoint signaling | NA | NA | 5.31e-05 | NA |
| GO:0071174 | mitotic spindle checkpoint signaling | NA | NA | 5.31e-05 | NA |
| GO:0051784 | negative regulation of nuclear division | NA | NA | 6.58e-05 | NA |
| GO:0030261 | chromosome condensation | NA | NA | 8.70e-05 | NA |
| GO:0080135 | regulation of cellular response to stres... | NA | NA | 9.03e-05 | NA |
| GO:0071459 | protein localization to chromosome, cent... | NA | NA | 9.66e-05 | NA |
| GO:0051783 | regulation of nuclear division | NA | NA | 9.68e-05 | NA |
| GO:0051306 | mitotic sister chromatid separation | NA | NA | 1.13e-04 | NA |
| GO:0045787 | positive regulation of cell cycle | NA | NA | 1.13e-04 | NA |
| GO:1902850 | microtubule cytoskeleton organization in... | NA | NA | 1.26e-04 | NA |
| GO:0051303 | establishment of chromosome localization | NA | NA | 1.79e-04 | NA |
| GO:0140013 | meiotic nuclear division | NA | NA | 1.88e-04 | NA |
| GO:0007051 | spindle organization | NA | NA | 1.88e-04 | NA |
| GO:0010965 | regulation of mitotic sister chromatid s... | NA | NA | 2.06e-04 | NA |
| GO:0008608 | attachment of spindle microtubules to ki... | NA | NA | 2.79e-04 | NA |
| GO:0050000 | chromosome localization | NA | NA | 2.95e-04 | NA |
| GO:0051225 | spindle assembly | NA | NA | 3.09e-04 | NA |
| GO:0044085 | cellular component biogenesis | NA | NA | 3.14e-04 | NA |
| GO:2001251 | negative regulation of chromosome organi... | NA | NA | 3.27e-04 | NA |
| GO:0051310 | metaphase chromosome alignment | NA | NA | 5.21e-04 | NA |
| GO:2000781 | positive regulation of double-strand bre... | NA | NA | 5.38e-04 | NA |
| GO:1901976 | regulation of cell cycle checkpoint | NA | NA | 8.14e-04 | NA |
| GO:0051988 | regulation of attachment of spindle micr... | NA | NA | 8.66e-04 | NA |
| GO:1901991 | negative regulation of mitotic cell cycl... | NA | NA | 1.01e-03 | NA |
| GO:0008156 | negative regulation of DNA replication | NA | NA | 1.02e-03 | NA |
| GO:1903046 | meiotic cell cycle process | NA | NA | 1.34e-03 | NA |
| GO:0007093 | mitotic cell cycle checkpoint signaling | NA | NA | 1.45e-03 | NA |
| GO:0045739 | positive regulation of DNA repair | NA | NA | 1.45e-03 | NA |
| GO:0043933 | protein-containing complex organization | NA | NA | 1.59e-03 | NA |
| GO:0034502 | protein localization to chromosome | NA | NA | 1.94e-03 | NA |
| GO:0051321 | meiotic cell cycle | NA | NA | 2.12e-03 | NA |
| GO:0031392 | regulation of prostaglandin biosynthetic... | NA | NA | 2.12e-03 | NA |
| GO:1902751 | positive regulation of cell cycle G2/M p... | NA | NA | 2.34e-03 | NA |
| GO:0010569 | regulation of double-strand break repair... | NA | NA | 2.35e-03 | NA |
| GO:0065003 | protein-containing complex assembly | NA | NA | 2.40e-03 | NA |
| GO:0042254 | ribosome biogenesis | NA | NA | 2.59e-03 | NA |
| GO:0045814 | negative regulation of gene expression, ... | NA | NA | 2.77e-03 | NA |
| GO:0051315 | attachment of mitotic spindle microtubul... | NA | NA | 3.25e-03 | NA |
| GO:0051955 | regulation of amino acid transport | NA | NA | 3.31e-03 | NA |
| GO:0061644 | protein localization to CENP-A containin... | NA | NA | 3.39e-03 | NA |
| GO:0031507 | heterochromatin formation | NA | NA | 3.80e-03 | NA |
| GO:0090307 | mitotic spindle assembly | NA | NA | 4.00e-03 | NA |
| GO:0000018 | regulation of DNA recombination | NA | NA | 4.05e-03 | NA |
| GO:0022607 | cellular component assembly | NA | NA | 4.05e-03 | NA |
| GO:0000022 | mitotic spindle elongation | NA | NA | 4.12e-03 | NA |
| GO:0051251 | positive regulation of lymphocyte activa... | NA | NA | 4.24e-03 | NA |
| GO:0033554 | cellular response to stress | NA | NA | 4.24e-03 | NA |
| GO:0051256 | mitotic spindle midzone assembly | NA | NA | 4.55e-03 | NA |
| GO:0097190 | apoptotic signaling pathway | NA | NA | 4.79e-03 | NA |
| GO:0051302 | regulation of cell division | NA | NA | 5.06e-03 | NA |
| GO:0010971 | positive regulation of G2/M transition o... | NA | NA | 5.06e-03 | NA |
| GO:0051231 | spindle elongation | NA | NA | 5.21e-03 | NA |
| GO:0022613 | ribonucleoprotein complex biogenesis | NA | NA | 5.29e-03 | NA |
| GO:0071479 | cellular response to ionizing radiation | NA | NA | 5.66e-03 | NA |
| GO:0070059 | intrinsic apoptotic signaling pathway in... | NA | NA | 6.03e-03 | NA |
| GO:0019731 | antibacterial humoral response | NA | NA | 6.38e-03 | NA |
| GO:0061982 | meiosis I cell cycle process | NA | NA | 7.29e-03 | NA |
| GO:0022409 | positive regulation of cell-cell adhesio... | NA | NA | 8.12e-03 | NA |
| GO:0007080 | mitotic metaphase chromosome alignment | NA | NA | 8.14e-03 | NA |
| GO:0034085 | establishment of sister chromatid cohesi... | NA | NA | 8.14e-03 | NA |
| GO:0097193 | intrinsic apoptotic signaling pathway | NA | NA | 8.69e-03 | NA |
| GO:0032890 | regulation of organic acid transport | NA | NA | 9.09e-03 | NA |
| GO:0010639 | negative regulation of organelle organiz... | NA | NA | 9.11e-03 | NA |
| GO:0030073 | insulin secretion | NA | NA | 9.14e-03 | NA |
| GO:0050870 | positive regulation of T cell activation | NA | NA | 9.25e-03 | NA |
| GO:0048522 | positive regulation of cellular process | NA | NA | 1.01e-02 | NA |
| GO:0014049 | positive regulation of glutamate secreti... | NA | NA | 1.02e-02 | NA |
| GO:0160049 | negative regulation of cGAS/STING signal... | NA | NA | 1.04e-02 | NA |
| GO:0045132 | meiotic chromosome segregation | NA | NA | 1.15e-02 | NA |
| GO:0071362 | cellular response to ether | NA | NA | 1.15e-02 | NA |
| GO:0000082 | G1/S transition of mitotic cell cycle | NA | NA | 1.16e-02 | NA |
| GO:0140896 | cGAS/STING signaling pathway | NA | NA | 1.17e-02 | NA |
| GO:0051255 | spindle midzone assembly | NA | NA | 1.21e-02 | NA |
| GO:0007076 | mitotic chromosome condensation | NA | NA | 1.33e-02 | NA |
| GO:0014048 | regulation of glutamate secretion | NA | NA | 1.34e-02 | NA |
| GO:0002696 | positive regulation of leukocyte activat... | NA | NA | 1.45e-02 | NA |
| GO:0034508 | centromere complex assembly | NA | NA | 1.47e-02 | NA |
| GO:2000045 | regulation of G1/S transition of mitotic... | NA | NA | 1.53e-02 | NA |
| GO:0001945 | lymph vessel development | NA | NA | 1.61e-02 | NA |
| GO:0016072 | rRNA metabolic process | NA | NA | 1.62e-02 | NA |
| GO:0062029 | positive regulation of stress granule as... | NA | NA | 1.62e-02 | NA |
| GO:0051249 | regulation of lymphocyte activation | NA | NA | 1.68e-02 | NA |
| GO:0006337 | nucleosome disassembly | NA | NA | 1.69e-02 | NA |
| GO:0006275 | regulation of DNA replication | NA | NA | 1.69e-02 | NA |
| GO:0022407 | regulation of cell-cell adhesion | NA | NA | 1.70e-02 | NA |
| GO:0044771 | meiotic cell cycle phase transition | NA | NA | 1.74e-02 | NA |
| GO:1901989 | positive regulation of cell cycle phase ... | NA | NA | 1.80e-02 | NA |
| GO:0032986 | protein-DNA complex disassembly | NA | NA | 1.81e-02 | NA |
| GO:0015833 | peptide transport | NA | NA | 1.87e-02 | NA |
| GO:0030072 | peptide hormone secretion | NA | NA | 1.87e-02 | NA |
| GO:0050867 | positive regulation of cell activation | NA | NA | 1.89e-02 | NA |
| GO:0071168 | protein localization to chromatin | NA | NA | 1.96e-02 | NA |
| GO:0044843 | cell cycle G1/S phase transition | NA | NA | 2.03e-02 | NA |
| GO:0002790 | peptide secretion | NA | NA | 2.04e-02 | NA |
| GO:0002791 | regulation of peptide secretion | NA | NA | 2.04e-02 | NA |
| GO:0090087 | regulation of peptide transport | NA | NA | 2.04e-02 | NA |
| GO:1902423 | regulation of attachment of mitotic spin... | NA | NA | 2.18e-02 | NA |
| GO:0051956 | negative regulation of amino acid transp... | NA | NA | 2.18e-02 | NA |
| GO:0043382 | positive regulation of memory T cell dif... | NA | NA | 2.28e-02 | NA |
| GO:0060623 | regulation of chromosome condensation | NA | NA | 2.36e-02 | NA |
| GO:1903039 | positive regulation of leukocyte cell-ce... | NA | NA | 2.36e-02 | NA |
| GO:0007019 | microtubule depolymerization | NA | NA | 2.36e-02 | NA |
| GO:1902806 | regulation of cell cycle G1/S phase tran... | NA | NA | 2.38e-02 | NA |
| GO:0007127 | meiosis I | NA | NA | 2.61e-02 | NA |
| GO:0050830 | defense response to Gram-positive bacter... | NA | NA | 2.64e-02 | NA |
| GO:2001244 | positive regulation of intrinsic apoptot... | NA | NA | 2.64e-02 | NA |
| GO:0009059 | macromolecule biosynthetic process | NA | NA | 2.64e-02 | NA |
| GO:0051053 | negative regulation of DNA metabolic pro... | NA | NA | 2.64e-02 | NA |
| GO:0008219 | cell death | NA | NA | 2.64e-02 | NA |
| GO:0034975 | protein folding in endoplasmic reticulum | NA | NA | 2.71e-02 | NA |
| GO:0006303 | double-strand break repair via nonhomolo... | NA | NA | 2.71e-02 | NA |
| GO:0006364 | rRNA processing | NA | NA | 2.71e-02 | NA |
| GO:0099174 | regulation of presynapse organization | NA | NA | 2.72e-02 | NA |
| GO:1905606 | regulation of presynapse assembly | NA | NA | 2.72e-02 | NA |
| GO:1901992 | positive regulation of mitotic cell cycl... | NA | NA | 2.83e-02 | NA |
| GO:0048518 | positive regulation of biological proces... | NA | NA | 2.97e-02 | NA |
| GO:0048245 | eosinophil chemotaxis | NA | NA | 3.01e-02 | NA |
| GO:0090231 | regulation of spindle checkpoint | NA | NA | 3.02e-02 | NA |
| GO:0043331 | response to dsRNA | NA | NA | 3.02e-02 | NA |
| GO:0002483 | antigen processing and presentation of e... | NA | NA | 3.05e-02 | NA |
| GO:0097278 | complement-dependent cytotoxicity | NA | NA | 3.17e-02 | NA |
| GO:0090276 | regulation of peptide hormone secretion | NA | NA | 3.17e-02 | NA |
| GO:0034087 | establishment of mitotic sister chromati... | NA | NA | 3.17e-02 | NA |
| GO:1902459 | positive regulation of stem cell populat... | NA | NA | 3.18e-02 | NA |
| GO:0072677 | eosinophil migration | NA | NA | 3.19e-02 | NA |
| GO:2000669 | negative regulation of dendritic cell ap... | NA | NA | 3.22e-02 | NA |
| GO:1905821 | positive regulation of chromosome conden... | NA | NA | 3.22e-02 | NA |
| GO:0045653 | negative regulation of megakaryocyte dif... | NA | NA | 3.22e-02 | NA |
| GO:0032465 | regulation of cytokinesis | NA | NA | 3.22e-02 | NA |
| GO:0071692 | protein localization to extracellular re... | NA | NA | 3.27e-02 | NA |
| GO:0098937 | anterograde dendritic transport | NA | NA | 3.29e-02 | NA |
| GO:0000375 | RNA splicing, via transesterification re... | NA | NA | 3.29e-02 | NA |
| GO:0007143 | female meiotic nuclear division | NA | NA | 3.33e-02 | NA |
| GO:0010829 | negative regulation of D-glucose transme... | NA | NA | 3.44e-02 | NA |
| GO:0035592 | establishment of protein localization to... | NA | NA | 3.54e-02 | NA |
| GO:1905820 | positive regulation of chromosome separa... | NA | NA | 3.54e-02 | NA |
| GO:2001235 | positive regulation of apoptotic signali... | NA | NA | 3.66e-02 | NA |
| GO:1901993 | regulation of meiotic cell cycle phase t... | NA | NA | 3.69e-02 | NA |
| GO:0045934 | negative regulation of nucleobase-contai... | NA | NA | 3.71e-02 | NA |
| GO:0080134 | regulation of response to stress | NA | NA | 3.91e-02 | NA |
| GO:0006997 | nucleus organization | NA | NA | 3.92e-02 | NA |
| GO:0051307 | meiotic chromosome separation | NA | NA | 3.92e-02 | NA |
| GO:0042104 | positive regulation of activated T cell ... | NA | NA | 3.96e-02 | NA |
| GO:0012501 | programmed cell death | NA | NA | 4.01e-02 | NA |
| GO:0009306 | protein secretion | NA | NA | 4.12e-02 | NA |
| GO:0032075 | positive regulation of nuclease activity | NA | NA | 4.20e-02 | NA |
| GO:0032467 | positive regulation of cytokinesis | NA | NA | 4.20e-02 | NA |
| GO:0090266 | regulation of mitotic cell cycle spindle... | NA | NA | 4.40e-02 | NA |
| GO:1903504 | regulation of mitotic spindle checkpoint | NA | NA | 4.40e-02 | NA |
| GO:0097421 | liver regeneration | NA | NA | 4.40e-02 | NA |
| GO:0032071 | regulation of endodeoxyribonuclease acti... | NA | NA | 4.47e-02 | NA |
| GO:0050796 | regulation of insulin secretion | NA | NA | 4.47e-02 | NA |
| GO:0031055 | chromatin remodeling at centromere | NA | NA | 4.47e-02 | NA |
| GO:0034080 | CENP-A containing chromatin assembly | NA | NA | 4.47e-02 | NA |
| GO:0045910 | negative regulation of DNA recombination | NA | NA | 4.47e-02 | NA |
| GO:0071868 | cellular response to monoamine stimulus | NA | NA | 4.47e-02 | NA |
| GO:0071870 | cellular response to catecholamine stimu... | NA | NA | 4.47e-02 | NA |
| GO:1903350 | response to dopamine | NA | NA | 4.47e-02 | NA |
| GO:0044806 | G-quadruplex DNA unwinding | NA | NA | 4.52e-02 | NA |
| GO:0098971 | anterograde dendritic transport of neuro... | NA | NA | 4.55e-02 | NA |
| GO:0071359 | cellular response to dsRNA | NA | NA | 4.64e-02 | NA |
| GO:0071103 | DNA conformation change | NA | NA | 4.72e-02 | NA |
| GO:0021999 | neural plate anterior/posterior regional... | NA | NA | 4.75e-02 | NA |
| GO:0006915 | apoptotic process | NA | NA | 4.75e-02 | NA |
| GO:0007062 | sister chromatid cohesion | NA | NA | 4.75e-02 | NA |
| GO:0042273 | ribosomal large subunit biogenesis | NA | NA | 4.75e-02 | NA |
| GO:0032392 | DNA geometric change | NA | NA | 4.75e-02 | NA |
| GO:0006271 | DNA strand elongation involved in DNA re... | NA | NA | 4.75e-02 | NA |
| GO:0010389 | regulation of G2/M transition of mitotic... | NA | NA | 4.75e-02 | NA |
| GO:2001293 | malonyl-CoA metabolic process | NA | NA | 4.79e-02 | NA |
| GO:0001946 | lymphangiogenesis | NA | NA | 4.79e-02 | NA |
| GO:0045911 | positive regulation of DNA recombination | NA | NA | 4.79e-02 | NA |
| GO:2000036 | regulation of stem cell population maint... | NA | NA | 4.79e-02 | NA |
| GO:2000330 | positive regulation of T-helper 17 cell ... | NA | NA | 4.91e-02 | NA |
| GO:2000035 | regulation of stem cell division | NA | NA | 4.93e-02 | NA |
| GO:1903294 | regulation of glutamate secretion, neuro... | NA | NA | 4.95e-02 | NA |
| GO:0035094 | response to nicotine | NA | NA | 4.95e-02 | NA |
| GO:0042749 | regulation of circadian sleep/wake cycle | NA | NA | 4.97e-02 | NA |
| GO:0006897 | endocytosis | NA | NA | NA | 2.41e-02 |
| GO:0098657 | import into cell | NA | NA | NA | 3.72e-02 |
| GO.ID | Term | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 |
|---|---|---|---|---|---|
| GO:0002181 | cytoplasmic translation | NA | NA | 7.84e-15 | 1.44e-12 |
| GO:0006412 | translation | NA | NA | 6.33e-09 | 1.07e-07 |
| GO:0001906 | cell killing | NA | NA | 3.85e-05 | 8.34e-03 |
| GO:0002399 | MHC class II protein complex assembly | NA | NA | 3.85e-05 | 6.30e-03 |
| GO:0002503 | peptide antigen assembly with MHC class ... | NA | NA | 3.85e-05 | 6.30e-03 |
| GO:0019882 | antigen processing and presentation | NA | NA | 1.14e-04 | 5.62e-05 |
| GO:0061844 | antimicrobial humoral immune response me... | NA | NA | 1.20e-04 | 5.51e-03 |
| GO:0044419 | biological process involved in interspec... | NA | NA | 1.22e-04 | 9.42e-03 |
| GO:0019730 | antimicrobial humoral response | NA | NA | 1.98e-04 | 2.34e-03 |
| GO:0043207 | response to external biotic stimulus | NA | NA | 1.98e-04 | 2.34e-02 |
| GO:0051707 | response to other organism | NA | NA | 1.98e-04 | 2.34e-02 |
| GO:0048002 | antigen processing and presentation of p... | NA | NA | 3.15e-04 | 1.19e-04 |
| GO:0009607 | response to biotic stimulus | NA | NA | 3.15e-04 | 2.72e-02 |
| GO:0019884 | antigen processing and presentation of e... | NA | NA | 3.15e-04 | 1.35e-03 |
| GO:0002504 | antigen processing and presentation of p... | NA | NA | 5.31e-04 | 3.04e-03 |
| GO:0006959 | humoral immune response | NA | NA | 5.69e-04 | 1.14e-02 |
| GO:0042110 | T cell activation | NA | NA | 7.42e-04 | 2.72e-02 |
| GO:0002495 | antigen processing and presentation of p... | NA | NA | 8.26e-04 | 3.21e-03 |
| GO:0002396 | MHC protein complex assembly | NA | NA | 8.26e-04 | 6.30e-03 |
| GO:0002501 | peptide antigen assembly with MHC protei... | NA | NA | 8.26e-04 | 6.30e-03 |
| GO:0002478 | antigen processing and presentation of e... | NA | NA | 9.49e-04 | 3.41e-03 |
| GO:0019886 | antigen processing and presentation of e... | NA | NA | 1.59e-03 | 8.56e-03 |
| GO:0019883 | antigen processing and presentation of e... | NA | NA | 2.02e-03 | 1.83e-02 |
| GO:0019538 | protein metabolic process | NA | NA | 2.14e-03 | NA |
| GO:0002250 | adaptive immune response | NA | NA | 2.14e-03 | 1.74e-02 |
| GO:0006952 | defense response | NA | NA | 2.31e-03 | NA |
| GO:0050863 | regulation of T cell activation | NA | NA | 2.31e-03 | 2.72e-02 |
| GO:0046649 | lymphocyte activation | NA | NA | 2.39e-03 | 2.72e-02 |
| GO:0002376 | immune system process | NA | NA | 2.39e-03 | 2.83e-02 |
| GO:0043069 | negative regulation of programmed cell d... | NA | NA | 2.39e-03 | 6.30e-03 |
| GO:0009605 | response to external stimulus | NA | NA | 2.60e-03 | NA |
| GO:0097190 | apoptotic signaling pathway | NA | NA | 3.00e-03 | 3.15e-02 |
| GO:0022407 | regulation of cell-cell adhesion | NA | NA | 3.04e-03 | 2.07e-02 |
| GO:0043067 | regulation of programmed cell death | NA | NA | 3.04e-03 | 2.72e-02 |
| GO:0019731 | antibacterial humoral response | NA | NA | 3.30e-03 | 4.48e-02 |
| GO:0042127 | regulation of cell population proliferat... | NA | NA | 3.30e-03 | 4.48e-02 |
| GO:0042274 | ribosomal small subunit biogenesis | NA | NA | 3.39e-03 | 2.72e-02 |
| GO:0001819 | positive regulation of cytokine producti... | NA | NA | 3.39e-03 | NA |
| GO:0006413 | translational initiation | NA | NA | 3.49e-03 | 2.72e-02 |
| GO:0001913 | T cell mediated cytotoxicity | NA | NA | 3.49e-03 | 4.77e-02 |
| GO:0043066 | negative regulation of apoptotic process | NA | NA | 3.49e-03 | 5.80e-03 |
| GO:0006955 | immune response | NA | NA | 3.49e-03 | 2.83e-02 |
| GO:0008219 | cell death | NA | NA | 3.49e-03 | 2.34e-02 |
| GO:0050830 | defense response to Gram-positive bacter... | NA | NA | 3.51e-03 | 3.85e-02 |
| GO:0098609 | cell-cell adhesion | NA | NA | 3.51e-03 | 2.07e-02 |
| GO:1903037 | regulation of leukocyte cell-cell adhesi... | NA | NA | 3.54e-03 | 3.85e-02 |
| GO:0098542 | defense response to other organism | NA | NA | 4.15e-03 | NA |
| GO:0051249 | regulation of lymphocyte activation | NA | NA | 4.15e-03 | 3.96e-02 |
| GO:0048584 | positive regulation of response to stimu... | NA | NA | 4.83e-03 | NA |
| GO:0006334 | nucleosome assembly | NA | NA | 4.83e-03 | 6.95e-03 |
| GO:0031640 | killing of cells of another organism | NA | NA | 4.83e-03 | 2.72e-02 |
| GO:0141061 | disruption of cell in another organism | NA | NA | 4.83e-03 | 2.72e-02 |
| GO:0002684 | positive regulation of immune system pro... | NA | NA | 4.83e-03 | NA |
| GO:0012501 | programmed cell death | NA | NA | 5.10e-03 | 3.14e-02 |
| GO:0022409 | positive regulation of cell-cell adhesio... | NA | NA | 5.10e-03 | 2.34e-02 |
| GO:0050870 | positive regulation of T cell activation | NA | NA | 5.62e-03 | 1.74e-02 |
| GO:0140546 | defense response to symbiont | NA | NA | 5.63e-03 | NA |
| GO:0042981 | regulation of apoptotic process | NA | NA | 5.73e-03 | 3.15e-02 |
| GO:1903039 | positive regulation of leukocyte cell-ce... | NA | NA | 5.93e-03 | 2.34e-02 |
| GO:0006508 | proteolysis | NA | NA | 6.09e-03 | NA |
| GO:0006915 | apoptotic process | NA | NA | 6.09e-03 | 3.14e-02 |
| GO:2001242 | regulation of intrinsic apoptotic signal... | NA | NA | 6.09e-03 | 1.42e-02 |
| GO:2001233 | regulation of apoptotic signaling pathwa... | NA | NA | 6.09e-03 | NA |
| GO:0045321 | leukocyte activation | NA | NA | 6.36e-03 | 3.15e-02 |
| GO:0032609 | type II interferon production | NA | NA | 6.36e-03 | 1.15e-02 |
| GO:0032649 | regulation of type II interferon product... | NA | NA | 6.36e-03 | 1.15e-02 |
| GO:0007159 | leukocyte cell-cell adhesion | NA | NA | 6.56e-03 | 3.44e-02 |
| GO:0050865 | regulation of cell activation | NA | NA | 8.04e-03 | NA |
| GO:0097529 | myeloid leukocyte migration | NA | NA | 8.08e-03 | 4.77e-02 |
| GO:0008284 | positive regulation of cell population p... | NA | NA | 8.50e-03 | NA |
| GO:0034975 | protein folding in endoplasmic reticulum | NA | NA | 9.43e-03 | 4.08e-02 |
| GO:0002694 | regulation of leukocyte activation | NA | NA | 1.00e-02 | NA |
| GO:0008283 | cell population proliferation | NA | NA | 1.02e-02 | NA |
| GO:0051955 | regulation of amino acid transport | NA | NA | 1.03e-02 | 2.34e-02 |
| GO:0090025 | regulation of monocyte chemotaxis | NA | NA | 1.06e-02 | NA |
| GO:0009617 | response to bacterium | NA | NA | 1.06e-02 | NA |
| GO:0065004 | protein-DNA complex assembly | NA | NA | 1.16e-02 | 2.31e-02 |
| GO:0002437 | inflammatory response to antigenic stimu... | NA | NA | 1.19e-02 | 4.26e-02 |
| GO:0051251 | positive regulation of lymphocyte activa... | NA | NA | 1.21e-02 | 3.15e-02 |
| GO:0034087 | establishment of mitotic sister chromati... | NA | NA | 1.21e-02 | NA |
| GO:0141060 | disruption of anatomical structure in an... | NA | NA | 1.24e-02 | NA |
| GO:0002696 | positive regulation of leukocyte activat... | NA | NA | 1.29e-02 | 4.08e-02 |
| GO:0002682 | regulation of immune system process | NA | NA | 1.32e-02 | NA |
| GO:0050867 | positive regulation of cell activation | NA | NA | 1.33e-02 | 3.56e-02 |
| GO:0071824 | protein-DNA complex organization | NA | NA | 1.33e-02 | 3.15e-02 |
| GO:0050729 | positive regulation of inflammatory resp... | NA | NA | 1.39e-02 | 2.72e-02 |
| GO:0034728 | nucleosome organization | NA | NA | 1.47e-02 | 3.56e-02 |
| GO:0071345 | cellular response to cytokine stimulus | NA | NA | 1.54e-02 | 4.81e-02 |
| GO:0001775 | cell activation | NA | NA | 1.54e-02 | NA |
| GO:0042129 | regulation of T cell proliferation | NA | NA | 1.54e-02 | NA |
| GO:0042254 | ribosome biogenesis | NA | NA | 1.63e-02 | 3.49e-02 |
| GO:0015959 | diadenosine polyphosphate metabolic proc... | NA | NA | 1.65e-02 | NA |
| GO:0002698 | negative regulation of immune effector p... | NA | NA | 1.76e-02 | 4.36e-02 |
| GO:0031341 | regulation of cell killing | NA | NA | 1.76e-02 | NA |
| GO:0002697 | regulation of immune effector process | NA | NA | 1.88e-02 | NA |
| GO:0001909 | leukocyte mediated cytotoxicity | NA | NA | 1.88e-02 | NA |
| GO:0032944 | regulation of mononuclear cell prolifera... | NA | NA | 1.93e-02 | NA |
| GO:0002711 | positive regulation of T cell mediated i... | NA | NA | 1.93e-02 | NA |
| GO:0030162 | regulation of proteolysis | NA | NA | 1.95e-02 | NA |
| GO:0001916 | positive regulation of T cell mediated c... | NA | NA | 2.14e-02 | NA |
| GO:1901652 | response to peptide | NA | NA | 2.14e-02 | NA |
| GO:0031343 | positive regulation of cell killing | NA | NA | 2.14e-02 | NA |
| GO:0034109 | homotypic cell-cell adhesion | NA | NA | 2.14e-02 | 3.15e-02 |
| GO:0035094 | response to nicotine | NA | NA | 2.15e-02 | 3.15e-02 |
| GO:0080134 | regulation of response to stress | NA | NA | 2.18e-02 | NA |
| GO:0051246 | regulation of protein metabolic process | NA | NA | 2.18e-02 | NA |
| GO:0002456 | T cell mediated immunity | NA | NA | 2.26e-02 | NA |
| GO:2000767 | positive regulation of cytoplasmic trans... | NA | NA | 2.26e-02 | NA |
| GO:0034976 | response to endoplasmic reticulum stress | NA | NA | 2.26e-02 | NA |
| GO:0002709 | regulation of T cell mediated immunity | NA | NA | 2.26e-02 | NA |
| GO:0070663 | regulation of leukocyte proliferation | NA | NA | 2.26e-02 | NA |
| GO:0043331 | response to dsRNA | NA | NA | 2.30e-02 | 4.77e-02 |
| GO:0002483 | antigen processing and presentation of e... | NA | NA | 2.32e-02 | NA |
| GO:0110076 | negative regulation of ferroptosis | NA | NA | 2.35e-02 | NA |
| GO:0031204 | post-translational protein targeting to ... | NA | NA | 2.80e-02 | NA |
| GO:0050670 | regulation of lymphocyte proliferation | NA | NA | 2.89e-02 | NA |
| GO:0002443 | leukocyte mediated immunity | NA | NA | 2.96e-02 | NA |
| GO:0007056 | spindle assembly involved in female meio... | NA | NA | 2.96e-02 | NA |
| GO:0030097 | hemopoiesis | NA | NA | 2.96e-02 | NA |
| GO:0045087 | innate immune response | NA | NA | 3.04e-02 | NA |
| GO:0051603 | proteolysis involved in protein cataboli... | NA | NA | 3.04e-02 | NA |
| GO:0050778 | positive regulation of immune response | NA | NA | 3.17e-02 | NA |
| GO:0032757 | positive regulation of interleukin-8 pro... | NA | NA | 3.18e-02 | NA |
| GO:1902235 | regulation of endoplasmic reticulum stre... | NA | NA | 3.19e-02 | NA |
| GO:0002449 | lymphocyte mediated immunity | NA | NA | 3.35e-02 | NA |
| GO:0034097 | response to cytokine | NA | NA | 3.35e-02 | NA |
| GO:0000280 | nuclear division | NA | NA | 3.39e-02 | NA |
| GO:0050727 | regulation of inflammatory response | NA | NA | 3.44e-02 | 4.81e-02 |
| GO:0050776 | regulation of immune response | NA | NA | 3.49e-02 | NA |
| GO:0001817 | regulation of cytokine production | NA | NA | 3.72e-02 | NA |
| GO:0016485 | protein processing | NA | NA | 3.77e-02 | NA |
| GO:0007080 | mitotic metaphase chromosome alignment | NA | NA | 3.85e-02 | NA |
| GO:0002252 | immune effector process | NA | NA | 3.87e-02 | NA |
| GO:0002835 | negative regulation of response to tumor... | NA | NA | 3.89e-02 | NA |
| GO:0002838 | negative regulation of immune response t... | NA | NA | 3.89e-02 | NA |
| GO:0001914 | regulation of T cell mediated cytotoxici... | NA | NA | 3.92e-02 | NA |
| GO:0140014 | mitotic nuclear division | NA | NA | 3.92e-02 | 4.12e-02 |
| GO:0002683 | negative regulation of immune system pro... | NA | NA | 3.92e-02 | NA |
| GO:0048285 | organelle fission | NA | NA | 3.93e-02 | NA |
| GO:0043933 | protein-containing complex organization | NA | NA | 4.02e-02 | 2.66e-02 |
| GO:0072599 | establishment of protein localization to... | NA | NA | 4.31e-02 | NA |
| GO:0002474 | antigen processing and presentation of p... | NA | NA | 4.31e-02 | 3.15e-02 |
| GO:0065003 | protein-containing complex assembly | NA | NA | 4.44e-02 | 1.04e-02 |
| GO:0097530 | granulocyte migration | NA | NA | 4.46e-02 | NA |
| GO:0042102 | positive regulation of T cell proliferat... | NA | NA | 4.47e-02 | NA |
| GO:0002286 | T cell activation involved in immune res... | NA | NA | 4.53e-02 | 2.84e-02 |
| GO:0001816 | cytokine production | NA | NA | 4.62e-02 | NA |
| GO:0032689 | negative regulation of type II interfero... | NA | NA | 4.62e-02 | 2.72e-02 |
| GO:0050777 | negative regulation of immune response | NA | NA | 4.69e-02 | NA |
| GO:0030163 | protein catabolic process | NA | NA | 4.69e-02 | NA |
| GO:0010628 | positive regulation of gene expression | NA | NA | 4.69e-02 | NA |
| GO:0097193 | intrinsic apoptotic signaling pathway | NA | NA | 4.69e-02 | NA |
| GO:0072677 | eosinophil migration | NA | NA | 4.69e-02 | 3.85e-02 |
| GO:2001234 | negative regulation of apoptotic signali... | NA | NA | 4.82e-02 | NA |
| GO:0031099 | regeneration | NA | NA | 4.86e-02 | 2.72e-02 |
| GO:1902253 | regulation of intrinsic apoptotic signal... | NA | NA | 4.86e-02 | NA |
| GO:0045839 | negative regulation of mitotic nuclear d... | NA | NA | 4.89e-02 | NA |
| GO:0048522 | positive regulation of cellular process | NA | NA | 4.89e-02 | NA |
| GO:0045047 | protein targeting to ER | NA | NA | 4.89e-02 | NA |
| GO:0006119 | oxidative phosphorylation | NA | NA | NA | 7.21e-03 |
| GO:0000070 | mitotic sister chromatid segregation | NA | NA | NA | 2.14e-02 |
| GO:0089718 | amino acid import across plasma membrane | NA | NA | NA | 2.31e-02 |
| GO:0000819 | sister chromatid segregation | NA | NA | NA | 2.72e-02 |
| GO:0042773 | ATP synthesis coupled electron transport | NA | NA | NA | 2.72e-02 |
| GO:0042775 | mitochondrial ATP synthesis coupled elec... | NA | NA | NA | 2.72e-02 |
| GO:0022613 | ribonucleoprotein complex biogenesis | NA | NA | NA | 2.83e-02 |
| GO:0032890 | regulation of organic acid transport | NA | NA | NA | 3.15e-02 |
| GO:1902622 | regulation of neutrophil migration | NA | NA | NA | 4.08e-02 |
| GO:1902624 | positive regulation of neutrophil migrat... | NA | NA | NA | 4.36e-02 |
| GO:0048524 | positive regulation of viral process | NA | NA | NA | 4.77e-02 |
| GO:0035265 | organ growth | NA | NA | NA | 4.81e-02 |
| GO:0015800 | acidic amino acid transport | NA | NA | NA | 4.88e-02 |
| GO.ID | Term | positive.PC.1 | negative.PC.1 | positive.PC.2 | negative.PC.2 |
|---|---|---|---|---|---|
| GO:0050776 | regulation of immune response | 1.29e-02 | NA | NA | NA |
| GO:0050778 | positive regulation of immune response | 1.29e-02 | NA | NA | NA |
| GO:0006508 | proteolysis | 3.04e-02 | NA | NA | NA |
| GO:0006955 | immune response | 3.04e-02 | NA | NA | NA |
| GO:0016043 | cellular component organization | 3.04e-02 | NA | NA | NA |
| GO:0071840 | cellular component organization or bioge... | 3.04e-02 | NA | NA | NA |
| GO:0022607 | cellular component assembly | 3.04e-02 | NA | NA | NA |
| GO:0044085 | cellular component biogenesis | 3.04e-02 | NA | NA | NA |
| GO:0043933 | protein-containing complex organization | 3.04e-02 | NA | NA | NA |
| GO:0065003 | protein-containing complex assembly | 3.04e-02 | NA | NA | NA |
| GO:0009891 | positive regulation of biosynthetic proc... | 3.04e-02 | NA | NA | NA |
| GO:0010557 | positive regulation of macromolecule bio... | 3.04e-02 | NA | NA | NA |
| GO:0010604 | positive regulation of macromolecule met... | 3.04e-02 | NA | NA | NA |
| GO:0031325 | positive regulation of cellular metaboli... | 3.04e-02 | NA | NA | NA |
| GO:0031328 | positive regulation of cellular biosynth... | 3.04e-02 | NA | NA | NA |
| GO:0048584 | positive regulation of response to stimu... | 3.64e-02 | NA | NA | NA |
| GO:0006950 | response to stress | 3.66e-02 | NA | NA | NA |
| GO:0009893 | positive regulation of metabolic process | 3.66e-02 | NA | NA | NA |
| GO:0007267 | cell-cell signaling | 3.90e-02 | NA | NA | NA |
| GO:0001775 | cell activation | 3.90e-02 | NA | NA | NA |
| GO:0045321 | leukocyte activation | 3.90e-02 | NA | NA | NA |
| GO:0051128 | regulation of cellular component organiz... | 3.90e-02 | NA | NA | NA |
| GO:0002682 | regulation of immune system process | 4.13e-02 | NA | NA | NA |
| GO:0002684 | positive regulation of immune system pro... | 4.13e-02 | NA | NA | NA |
| GO:0030154 | cell differentiation | 4.93e-02 | NA | NA | NA |
| GO:0048869 | cellular developmental process | 4.93e-02 | NA | NA | NA |
| GO:0048518 | positive regulation of biological proces... | 4.93e-02 | NA | NA | NA |
| GO:0050789 | regulation of biological process | NA | 2.33e-02 | NA | NA |
| GO:0065007 | biological regulation | NA | 2.33e-02 | NA | NA |
| GO:0050794 | regulation of cellular process | NA | 2.33e-02 | NA | NA |
| GO:0009987 | cellular process | NA | 3.54e-02 | NA | NA |
| GO.ID | Term | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 |
|---|---|---|---|---|---|
| GO:0006508 | proteolysis | NA | 4.4e-02 | NA | NA |
| GO:0019538 | protein metabolic process | NA | 4.7e-02 | NA | NA |
| GO.ID | Term | positive.PC.1 | negative.PC.1 | positive.PC.2 | negative.PC.2 |
|---|---|---|---|---|---|
| GO:0070062 | extracellular exosome | 5.39e-32 | NA | NA | NA |
| GO:1903561 | extracellular vesicle | 5.39e-32 | NA | NA | NA |
| GO:0043230 | extracellular organelle | 5.39e-32 | NA | NA | NA |
| GO:0065010 | extracellular membrane-bounded organelle | 5.39e-32 | NA | NA | NA |
| GO:0044391 | ribosomal subunit | 1.04e-28 | NA | 1.78e-02 | NA |
| GO:0022625 | cytosolic large ribosomal subunit | 2.80e-27 | NA | 1.73e-05 | NA |
| GO:0005615 | extracellular space | 3.55e-27 | NA | NA | NA |
| GO:0005576 | extracellular region | 1.99e-25 | NA | NA | NA |
| GO:0031982 | vesicle | 2.50e-22 | NA | NA | NA |
| GO:0022626 | cytosolic ribosome | 1.05e-21 | NA | 2.78e-07 | NA |
| GO:0005840 | ribosome | 9.28e-21 | NA | 1.88e-03 | NA |
| GO:0015934 | large ribosomal subunit | 1.63e-20 | NA | 4.69e-02 | NA |
| GO:0031090 | organelle membrane | 5.62e-14 | NA | NA | NA |
| GO:0005783 | endoplasmic reticulum | 1.20e-13 | NA | NA | NA |
| GO:0098796 | membrane protein complex | 4.62e-12 | NA | NA | NA |
| GO:0030141 | secretory granule | 1.02e-11 | NA | NA | NA |
| GO:0012505 | endomembrane system | 1.26e-11 | NA | NA | NA |
| GO:0022627 | cytosolic small ribosomal subunit | 3.61e-11 | NA | NA | NA |
| GO:0099503 | secretory vesicle | 8.39e-11 | NA | NA | NA |
| GO:0098588 | bounding membrane of organelle | 1.33e-10 | NA | NA | NA |
| GO:0000323 | lytic vacuole | 3.00e-10 | NA | NA | NA |
| GO:0005764 | lysosome | 3.00e-10 | NA | NA | NA |
| GO:0015935 | small ribosomal subunit | 1.64e-09 | NA | NA | NA |
| GO:0031410 | cytoplasmic vesicle | 4.75e-09 | NA | NA | NA |
| GO:0097708 | intracellular vesicle | 8.60e-09 | NA | NA | NA |
| GO:0016020 | membrane | 9.51e-09 | NA | NA | NA |
| GO:0005773 | vacuole | 2.17e-08 | NA | NA | NA |
| GO:0005789 | endoplasmic reticulum membrane | 2.17e-08 | NA | NA | NA |
| GO:0042175 | nuclear outer membrane-endoplasmic retic... | 2.65e-08 | NA | NA | NA |
| GO:0098827 | endoplasmic reticulum subcompartment | 3.11e-08 | NA | NA | NA |
| GO:0031984 | organelle subcompartment | 5.16e-08 | NA | NA | NA |
| GO:0035577 | azurophil granule membrane | 5.16e-08 | NA | NA | NA |
| GO:1990904 | ribonucleoprotein complex | 1.44e-07 | NA | 1.88e-03 | NA |
| GO:0005766 | primary lysosome | 2.23e-07 | NA | NA | NA |
| GO:0042582 | azurophil granule | 2.23e-07 | NA | NA | NA |
| GO:0030659 | cytoplasmic vesicle membrane | 3.84e-07 | NA | NA | NA |
| GO:0000139 | Golgi membrane | 3.84e-07 | NA | NA | NA |
| GO:0005740 | mitochondrial envelope | 5.15e-07 | NA | NA | NA |
| GO:0030667 | secretory granule membrane | 7.11e-07 | NA | NA | NA |
| GO:0005774 | vacuolar membrane | 9.39e-07 | NA | NA | NA |
| GO:0031966 | mitochondrial membrane | 9.39e-07 | NA | NA | NA |
| GO:0012506 | vesicle membrane | 9.43e-07 | NA | NA | NA |
| GO:0005765 | lysosomal membrane | 1.01e-06 | NA | NA | NA |
| GO:0098852 | lytic vacuole membrane | 1.01e-06 | NA | NA | NA |
| GO:0042611 | MHC protein complex | 1.03e-06 | NA | 9.35e-06 | NA |
| GO:0098803 | respiratory chain complex | 1.18e-06 | NA | NA | NA |
| GO:0019866 | organelle inner membrane | 1.37e-06 | NA | NA | NA |
| GO:0030133 | transport vesicle | 1.87e-06 | NA | NA | NA |
| GO:0005925 | focal adhesion | 2.17e-06 | NA | NA | NA |
| GO:0030055 | cell-substrate junction | 2.17e-06 | NA | NA | NA |
| GO:0005743 | mitochondrial inner membrane | 3.01e-06 | NA | NA | NA |
| GO:0009986 | cell surface | 3.01e-06 | NA | NA | NA |
| GO:0030135 | coated vesicle | 4.22e-06 | NA | NA | NA |
| GO:0030662 | coated vesicle membrane | 5.74e-06 | NA | NA | NA |
| GO:0098552 | side of membrane | 1.01e-05 | NA | NA | NA |
| GO:0042613 | MHC class II protein complex | 1.01e-05 | NA | 8.02e-06 | NA |
| GO:0042470 | melanosome | 1.04e-05 | NA | NA | NA |
| GO:0048770 | pigment granule | 1.04e-05 | NA | NA | NA |
| GO:0098798 | mitochondrial protein-containing complex | 1.21e-05 | NA | NA | NA |
| GO:0016469 | proton-transporting two-sector ATPase co... | 2.22e-05 | NA | NA | NA |
| GO:0005839 | proteasome core complex | 2.28e-05 | NA | NA | NA |
| GO:0101002 | ficolin-1-rich granule | 5.75e-05 | NA | NA | NA |
| GO:0031983 | vesicle lumen | 6.19e-05 | NA | NA | NA |
| GO:0060205 | cytoplasmic vesicle lumen | 6.19e-05 | NA | NA | NA |
| GO:0034774 | secretory granule lumen | 7.73e-05 | NA | NA | NA |
| GO:1990351 | transporter complex | 1.67e-04 | NA | NA | NA |
| GO:0090533 | cation-transporting ATPase complex | 2.14e-04 | NA | NA | NA |
| GO:0000315 | organellar large ribosomal subunit | 2.15e-04 | NA | NA | NA |
| GO:0005762 | mitochondrial large ribosomal subunit | 2.15e-04 | NA | NA | NA |
| GO:0070820 | tertiary granule | 2.37e-04 | NA | NA | NA |
| GO:0009897 | external side of plasma membrane | 2.52e-04 | NA | NA | NA |
| GO:0031967 | organelle envelope | 2.57e-04 | NA | NA | NA |
| GO:0031902 | late endosome membrane | 2.62e-04 | NA | NA | NA |
| GO:0005739 | mitochondrion | 2.92e-04 | NA | NA | NA |
| GO:1904813 | ficolin-1-rich granule lumen | 2.93e-04 | NA | NA | NA |
| GO:0005775 | vacuolar lumen | 3.47e-04 | NA | NA | NA |
| GO:0010008 | endosome membrane | 3.55e-04 | NA | NA | NA |
| GO:0030665 | clathrin-coated vesicle membrane | 4.44e-04 | NA | NA | NA |
| GO:0098857 | membrane microdomain | 4.67e-04 | NA | NA | NA |
| GO:0005737 | cytoplasm | 4.67e-04 | NA | NA | NA |
| GO:0045335 | phagocytic vesicle | 5.50e-04 | NA | NA | NA |
| GO:0000313 | organellar ribosome | 5.50e-04 | NA | NA | NA |
| GO:0005761 | mitochondrial ribosome | 5.50e-04 | NA | NA | NA |
| GO:0033178 | proton-transporting two-sector ATPase co... | 5.52e-04 | NA | NA | NA |
| GO:0005794 | Golgi apparatus | 5.97e-04 | NA | NA | NA |
| GO:1902495 | transmembrane transporter complex | 7.04e-04 | NA | NA | NA |
| GO:0030666 | endocytic vesicle membrane | 7.81e-04 | NA | NA | NA |
| GO:0030134 | COPII-coated ER to Golgi transport vesic... | 8.70e-04 | NA | 4.58e-02 | NA |
| GO:0045121 | membrane raft | 8.85e-04 | NA | NA | NA |
| GO:0034361 | very-low-density lipoprotein particle | 1.46e-03 | NA | NA | NA |
| GO:0034385 | triglyceride-rich plasma lipoprotein par... | 1.46e-03 | NA | NA | NA |
| GO:0030669 | clathrin-coated endocytic vesicle membra... | 1.60e-03 | NA | NA | NA |
| GO:0043227 | membrane-bounded organelle | 1.63e-03 | NA | NA | NA |
| GO:0000502 | proteasome complex | 1.77e-03 | NA | NA | NA |
| GO:0005791 | rough endoplasmic reticulum | 2.18e-03 | NA | NA | NA |
| GO:1905369 | endopeptidase complex | 2.61e-03 | NA | NA | NA |
| GO:0005770 | late endosome | 2.61e-03 | NA | NA | NA |
| GO:0045259 | proton-transporting ATP synthase complex | 2.73e-03 | NA | NA | NA |
| GO:0030670 | phagocytic vesicle membrane | 2.98e-03 | NA | NA | NA |
| GO:0019774 | proteasome core complex, beta-subunit co... | 3.31e-03 | NA | 4.45e-02 | NA |
| GO:0030136 | clathrin-coated vesicle | 3.43e-03 | NA | NA | NA |
| GO:0000221 | vacuolar proton-transporting V-type ATPa... | 3.43e-03 | NA | NA | NA |
| GO:0033180 | proton-transporting V-type ATPase, V1 do... | 3.43e-03 | NA | NA | NA |
| GO:0098553 | lumenal side of endoplasmic reticulum me... | 3.44e-03 | NA | 4.50e-03 | NA |
| GO:0031588 | nucleotide-activated protein kinase comp... | 3.60e-03 | NA | NA | NA |
| GO:0033176 | proton-transporting V-type ATPase comple... | 3.60e-03 | NA | NA | NA |
| GO:0045334 | clathrin-coated endocytic vesicle | 4.01e-03 | NA | NA | NA |
| GO:0033116 | endoplasmic reticulum-Golgi intermediate... | 4.30e-03 | NA | NA | NA |
| GO:1904724 | tertiary granule lumen | 4.50e-03 | NA | NA | NA |
| GO:0140534 | endoplasmic reticulum protein-containing... | 4.76e-03 | NA | 1.03e-03 | NA |
| GO:0030663 | COPI-coated vesicle membrane | 4.86e-03 | NA | 1.78e-02 | NA |
| GO:0005787 | signal peptidase complex | 4.86e-03 | NA | NA | NA |
| GO:0045277 | respiratory chain complex IV | 5.09e-03 | NA | NA | NA |
| GO:0043231 | intracellular membrane-bounded organelle | 5.30e-03 | NA | NA | NA |
| GO:0030139 | endocytic vesicle | 5.36e-03 | NA | NA | NA |
| GO:0008290 | F-actin capping protein complex | 5.36e-03 | NA | NA | NA |
| GO:0098797 | plasma membrane protein complex | 5.42e-03 | NA | NA | NA |
| GO:0005793 | endoplasmic reticulum-Golgi intermediate... | 5.65e-03 | NA | NA | NA |
| GO:0030137 | COPI-coated vesicle | 5.86e-03 | NA | 3.18e-02 | NA |
| GO:0005788 | endoplasmic reticulum lumen | 6.08e-03 | NA | NA | NA |
| GO:0072562 | blood microparticle | 6.37e-03 | NA | NA | NA |
| GO:0030054 | cell junction | 7.23e-03 | NA | NA | NA |
| GO:0097197 | tetraspanin-enriched microdomain | 7.40e-03 | NA | NA | NA |
| GO:0005798 | Golgi-associated vesicle | 7.86e-03 | NA | NA | NA |
| GO:0031970 | organelle envelope lumen | 8.68e-03 | NA | NA | NA |
| GO:0062023 | collagen-containing extracellular matrix | 9.41e-03 | NA | NA | NA |
| GO:0005768 | endosome | 9.61e-03 | NA | NA | 3.38e-03 |
| GO:0012507 | ER to Golgi transport vesicle membrane | 9.78e-03 | NA | 1.80e-02 | NA |
| GO:0001772 | immunological synapse | 1.08e-02 | NA | NA | NA |
| GO:0045202 | synapse | 1.09e-02 | NA | NA | NA |
| GO:0016471 | vacuolar proton-transporting V-type ATPa... | 1.14e-02 | NA | NA | NA |
| GO:0042581 | specific granule | 1.28e-02 | NA | NA | NA |
| GO:0042612 | MHC class I protein complex | 1.30e-02 | NA | NA | NA |
| GO:0098533 | ATPase dependent transmembrane transport... | 1.37e-02 | NA | NA | NA |
| GO:0030658 | transport vesicle membrane | 1.37e-02 | NA | NA | NA |
| GO:0005758 | mitochondrial intermembrane space | 1.37e-02 | NA | NA | NA |
| GO:0070765 | gamma-secretase complex | 1.64e-02 | NA | NA | NA |
| GO:0071944 | cell periphery | 1.83e-02 | NA | NA | NA |
| GO:0005834 | heterotrimeric G-protein complex | 1.86e-02 | NA | 3.92e-02 | NA |
| GO:0035578 | azurophil granule lumen | 1.86e-02 | NA | NA | NA |
| GO:0019773 | proteasome core complex, alpha-subunit c... | 2.19e-02 | NA | NA | NA |
| GO:0031904 | endosome lumen | 2.19e-02 | NA | NA | NA |
| GO:0005886 | plasma membrane | 2.28e-02 | NA | NA | NA |
| GO:0030312 | external encapsulating structure | 2.61e-02 | NA | NA | NA |
| GO:0031012 | extracellular matrix | 2.61e-02 | NA | NA | NA |
| GO:0140596 | TOM complex | 2.73e-02 | NA | NA | NA |
| GO:0070161 | anchoring junction | 3.01e-02 | NA | NA | NA |
| GO:0070937 | CRD-mediated mRNA stability complex | 3.04e-02 | NA | NA | NA |
| GO:0043202 | lysosomal lumen | 3.12e-02 | NA | NA | NA |
| GO:0044233 | mitochondria-associated endoplasmic reti... | 3.23e-02 | NA | NA | NA |
| GO:0098556 | cytoplasmic side of rough endoplasmic re... | 3.41e-02 | NA | NA | NA |
| GO:0071159 | NF-kappaB complex | 3.51e-02 | NA | NA | NA |
| GO:0098576 | lumenal side of membrane | 3.53e-02 | NA | 1.81e-02 | NA |
| GO:0030867 | rough endoplasmic reticulum membrane | 4.22e-02 | NA | NA | NA |
| GO:0008021 | synaptic vesicle | 4.22e-02 | NA | NA | NA |
| GO:0070069 | cytochrome complex | 4.69e-02 | NA | NA | NA |
| GO:0032040 | small-subunit processome | 4.79e-02 | NA | 4.58e-02 | NA |
| GO:0044322 | endoplasmic reticulum quality control co... | 4.84e-02 | NA | NA | NA |
| GO:0019897 | extrinsic component of plasma membrane | 4.84e-02 | NA | NA | NA |
| GO:0032991 | protein-containing complex | 4.92e-02 | NA | 4.84e-06 | NA |
| GO:0005694 | chromosome | NA | 4.22e-08 | 7.88e-20 | NA |
| GO:0043228 | non-membrane-bounded organelle | NA | 5.08e-07 | 1.30e-12 | NA |
| GO:0043232 | intracellular non-membrane-bounded organ... | NA | 5.08e-07 | 1.30e-12 | NA |
| GO:0005856 | cytoskeleton | NA | 5.08e-07 | 1.89e-02 | NA |
| GO:0005815 | microtubule organizing center | NA | 3.19e-06 | NA | NA |
| GO:0015630 | microtubule cytoskeleton | NA | 4.65e-06 | 1.45e-02 | NA |
| GO:0005814 | centriole | NA | 2.14e-05 | NA | NA |
| GO:0036064 | ciliary basal body | NA | 5.61e-05 | NA | NA |
| GO:0005654 | nucleoplasm | NA | 1.94e-04 | 1.79e-07 | NA |
| GO:0140513 | nuclear protein-containing complex | NA | 3.85e-04 | 2.97e-03 | NA |
| GO:0000228 | nuclear chromosome | NA | 5.15e-04 | 7.45e-04 | NA |
| GO:0031981 | nuclear lumen | NA | 8.40e-04 | 2.88e-09 | NA |
| GO:0005657 | replication fork | NA | 1.35e-03 | NA | NA |
| GO:0005813 | centrosome | NA | 1.43e-03 | NA | NA |
| GO:0000785 | chromatin | NA | 3.04e-03 | 1.95e-11 | NA |
| GO:0005634 | nucleus | NA | 5.27e-03 | 1.48e-07 | NA |
| GO:0031390 | Ctf18 RFC-like complex | NA | 9.21e-03 | NA | NA |
| GO:0071162 | CMG complex | NA | 1.06e-02 | NA | NA |
| GO:0031261 | DNA replication preinitiation complex | NA | 1.10e-02 | 2.75e-02 | NA |
| GO:0016607 | nuclear speck | NA | 1.17e-02 | NA | NA |
| GO:0005658 | alpha DNA polymerase:primase complex | NA | 1.51e-02 | NA | NA |
| GO:0016604 | nuclear body | NA | 1.51e-02 | NA | NA |
| GO:0034451 | centriolar satellite | NA | 1.60e-02 | NA | NA |
| GO:0099738 | cell cortex region | NA | 1.61e-02 | NA | NA |
| GO:0005663 | DNA replication factor C complex | NA | 2.47e-02 | NA | NA |
| GO:0035097 | histone methyltransferase complex | NA | 2.59e-02 | NA | NA |
| GO:0098687 | chromosomal region | NA | NA | 6.35e-14 | NA |
| GO:0000775 | chromosome, centromeric region | NA | NA | 7.97e-14 | NA |
| GO:0000786 | nucleosome | NA | NA | 7.71e-12 | NA |
| GO:0032993 | protein-DNA complex | NA | NA | 7.70e-11 | NA |
| GO:0000793 | condensed chromosome | NA | NA | 1.73e-10 | NA |
| GO:0000779 | condensed chromosome, centromeric region | NA | NA | 4.82e-08 | NA |
| GO:0000776 | kinetochore | NA | NA | 5.57e-08 | NA |
| GO:0034399 | nuclear periphery | NA | NA | 2.91e-05 | NA |
| GO:0000940 | outer kinetochore | NA | NA | 9.77e-05 | NA |
| GO:0005730 | nucleolus | NA | NA | 3.02e-04 | NA |
| GO:0034663 | endoplasmic reticulum chaperone complex | NA | NA | 3.57e-04 | NA |
| GO:0005819 | spindle | NA | NA | 4.12e-04 | NA |
| GO:0016363 | nuclear matrix | NA | NA | 6.18e-04 | NA |
| GO:0099080 | supramolecular complex | NA | NA | 6.18e-04 | NA |
| GO:0034506 | chromosome, centromeric core domain | NA | NA | 6.18e-04 | NA |
| GO:0031974 | membrane-enclosed lumen | NA | NA | 6.90e-04 | NA |
| GO:0043233 | organelle lumen | NA | NA | 6.90e-04 | NA |
| GO:0070013 | intracellular organelle lumen | NA | NA | 6.90e-04 | NA |
| GO:0045120 | pronucleus | NA | NA | 7.91e-04 | NA |
| GO:0000803 | sex chromosome | NA | NA | 1.18e-03 | NA |
| GO:0043505 | CENP-A containing nucleosome | NA | NA | 1.46e-03 | NA |
| GO:0061638 | CENP-A containing chromatin | NA | NA | 1.46e-03 | NA |
| GO:0070603 | SWI/SNF superfamily-type complex | NA | NA | 1.89e-03 | NA |
| GO:0010369 | chromocenter | NA | NA | 2.40e-03 | NA |
| GO:0001674 | female germ cell nucleus | NA | NA | 4.50e-03 | NA |
| GO:0001940 | male pronucleus | NA | NA | 4.50e-03 | NA |
| GO:0000781 | chromosome, telomeric region | NA | NA | 4.91e-03 | NA |
| GO:0001939 | female pronucleus | NA | NA | 5.56e-03 | NA |
| GO:0000922 | spindle pole | NA | NA | 6.57e-03 | NA |
| GO:0001741 | XY body | NA | NA | 7.54e-03 | NA |
| GO:0051233 | spindle midzone | NA | NA | 8.65e-03 | NA |
| GO:0032133 | chromosome passenger complex | NA | NA | 9.61e-03 | NA |
| GO:0072686 | mitotic spindle | NA | NA | 1.32e-02 | NA |
| GO:0005871 | kinesin complex | NA | NA | 1.45e-02 | NA |
| GO:0008250 | oligosaccharyltransferase complex | NA | NA | 1.48e-02 | NA |
| GO:0016514 | SWI/SNF complex | NA | NA | 1.54e-02 | NA |
| GO:0000939 | inner kinetochore | NA | NA | 1.57e-02 | NA |
| GO:0035060 | brahma complex | NA | NA | 1.62e-02 | NA |
| GO:0005881 | cytoplasmic microtubule | NA | NA | 1.62e-02 | NA |
| GO:0000796 | condensin complex | NA | NA | 1.66e-02 | NA |
| GO:1904949 | ATPase complex | NA | NA | 1.78e-02 | NA |
| GO:1902494 | catalytic complex | NA | NA | 1.80e-02 | NA |
| GO:0000794 | condensed nuclear chromosome | NA | NA | 1.81e-02 | NA |
| GO:0005874 | microtubule | NA | NA | 2.21e-02 | NA |
| GO:0071014 | post-mRNA release spliceosomal complex | NA | NA | 2.27e-02 | NA |
| GO:0097165 | nuclear stress granule | NA | NA | 2.36e-02 | NA |
| GO:0031234 | extrinsic component of cytoplasmic side ... | NA | NA | 2.43e-02 | NA |
| GO:0005652 | nuclear lamina | NA | NA | 3.18e-02 | NA |
| GO:0140288 | GBAF complex | NA | NA | 3.35e-02 | NA |
| GO:0097431 | mitotic spindle pole | NA | NA | 3.81e-02 | NA |
| GO:1990023 | mitotic spindle midzone | NA | NA | 3.92e-02 | NA |
| GO:0035861 | site of double-strand break | NA | NA | 3.92e-02 | NA |
| GO:0000930 | gamma-tubulin complex | NA | NA | 3.92e-02 | NA |
| GO:0000792 | heterochromatin | NA | NA | 3.92e-02 | NA |
| GO:0099513 | polymeric cytoskeletal fiber | NA | NA | 4.33e-02 | NA |
| GO:0005681 | spliceosomal complex | NA | NA | 4.34e-02 | NA |
| GO:0005784 | Sec61 translocon complex | NA | NA | 4.58e-02 | NA |
| GO:0071256 | translocon complex | NA | NA | 4.58e-02 | NA |
| GO:0001740 | Barr body | NA | NA | 4.58e-02 | NA |
| GO:0071013 | catalytic step 2 spliceosome | NA | NA | 4.91e-02 | NA |
| GO.ID | Term | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 |
|---|---|---|---|---|---|
| GO:0070062 | extracellular exosome | NA | NA | 1.95e-20 | 3.63e-16 |
| GO:1903561 | extracellular vesicle | NA | NA | 1.95e-20 | 3.63e-16 |
| GO:0043230 | extracellular organelle | NA | NA | 1.95e-20 | 3.64e-16 |
| GO:0065010 | extracellular membrane-bounded organelle | NA | NA | 1.95e-20 | 3.64e-16 |
| GO:0022626 | cytosolic ribosome | NA | NA | 4.53e-19 | 2.89e-15 |
| GO:0005615 | extracellular space | NA | NA | 6.82e-19 | 1.39e-13 |
| GO:0022625 | cytosolic large ribosomal subunit | NA | NA | 2.72e-18 | 3.53e-12 |
| GO:0044391 | ribosomal subunit | NA | NA | 1.02e-16 | 4.23e-14 |
| GO:0005576 | extracellular region | NA | NA | 2.17e-16 | 1.04e-11 |
| GO:0005840 | ribosome | NA | NA | 2.17e-16 | 4.78e-13 |
| GO:0015934 | large ribosomal subunit | NA | NA | 9.33e-13 | 2.23e-08 |
| GO:0042611 | MHC protein complex | NA | NA | 2.97e-10 | 7.83e-06 |
| GO:0031982 | vesicle | NA | NA | 2.95e-09 | 1.44e-08 |
| GO:1990904 | ribonucleoprotein complex | NA | NA | 7.87e-09 | 4.08e-07 |
| GO:0005783 | endoplasmic reticulum | NA | NA | 4.54e-08 | 2.49e-07 |
| GO:0005839 | proteasome core complex | NA | NA | 2.17e-07 | 3.14e-04 |
| GO:0042613 | MHC class II protein complex | NA | NA | 3.45e-07 | 1.50e-04 |
| GO:0000786 | nucleosome | NA | NA | 3.66e-07 | 1.44e-06 |
| GO:0000139 | Golgi membrane | NA | NA | 3.06e-06 | 1.50e-04 |
| GO:0000775 | chromosome, centromeric region | NA | NA | 4.39e-06 | 4.87e-05 |
| GO:0005789 | endoplasmic reticulum membrane | NA | NA | 4.54e-06 | 3.24e-06 |
| GO:0098827 | endoplasmic reticulum subcompartment | NA | NA | 4.79e-06 | 3.67e-06 |
| GO:0140534 | endoplasmic reticulum protein-containing... | NA | NA | 4.79e-06 | 1.08e-03 |
| GO:0022627 | cytosolic small ribosomal subunit | NA | NA | 5.08e-06 | 1.11e-06 |
| GO:0032991 | protein-containing complex | NA | NA | 1.28e-05 | 5.46e-06 |
| GO:0042175 | nuclear outer membrane-endoplasmic retic... | NA | NA | 1.28e-05 | 5.46e-06 |
| GO:0005925 | focal adhesion | NA | NA | 1.74e-05 | 7.48e-03 |
| GO:0030055 | cell-substrate junction | NA | NA | 1.74e-05 | 7.48e-03 |
| GO:0030663 | COPI-coated vesicle membrane | NA | NA | 2.08e-05 | 1.08e-03 |
| GO:0098796 | membrane protein complex | NA | NA | 2.64e-05 | 4.87e-05 |
| GO:0030133 | transport vesicle | NA | NA | 3.29e-05 | 8.31e-06 |
| GO:0015935 | small ribosomal subunit | NA | NA | 8.81e-05 | 5.75e-06 |
| GO:0031984 | organelle subcompartment | NA | NA | 2.03e-04 | 1.56e-04 |
| GO:0000221 | vacuolar proton-transporting V-type ATPa... | NA | NA | 3.09e-04 | 1.56e-02 |
| GO:0033180 | proton-transporting V-type ATPase, V1 do... | NA | NA | 3.09e-04 | 1.56e-02 |
| GO:0019774 | proteasome core complex, beta-subunit co... | NA | NA | 4.30e-04 | 9.66e-03 |
| GO:0030662 | coated vesicle membrane | NA | NA | 9.02e-04 | 1.71e-03 |
| GO:0098553 | lumenal side of endoplasmic reticulum me... | NA | NA | 1.07e-03 | 2.00e-04 |
| GO:0042612 | MHC class I protein complex | NA | NA | 1.07e-03 | NA |
| GO:0098552 | side of membrane | NA | NA | 1.07e-03 | 1.35e-02 |
| GO:0042470 | melanosome | NA | NA | 1.07e-03 | 2.89e-04 |
| GO:0048770 | pigment granule | NA | NA | 1.07e-03 | 2.89e-04 |
| GO:0012505 | endomembrane system | NA | NA | 1.15e-03 | 4.10e-03 |
| GO:0031234 | extrinsic component of cytoplasmic side ... | NA | NA | 1.15e-03 | 1.82e-03 |
| GO:0098687 | chromosomal region | NA | NA | 1.19e-03 | 1.94e-02 |
| GO:0016020 | membrane | NA | NA | 1.28e-03 | 7.48e-03 |
| GO:0032993 | protein-DNA complex | NA | NA | 1.31e-03 | 1.91e-03 |
| GO:0005834 | heterotrimeric G-protein complex | NA | NA | 1.57e-03 | 1.43e-03 |
| GO:0033178 | proton-transporting two-sector ATPase co... | NA | NA | 1.57e-03 | NA |
| GO:0000323 | lytic vacuole | NA | NA | 1.57e-03 | 2.29e-03 |
| GO:0005764 | lysosome | NA | NA | 1.57e-03 | 2.29e-03 |
| GO:0000776 | kinetochore | NA | NA | 1.62e-03 | 1.19e-02 |
| GO:0030137 | COPI-coated vesicle | NA | NA | 1.63e-03 | 7.97e-04 |
| GO:0000793 | condensed chromosome | NA | NA | 1.86e-03 | 1.94e-02 |
| GO:0030135 | coated vesicle | NA | NA | 1.89e-03 | 1.12e-02 |
| GO:0005737 | cytoplasm | NA | NA | 2.05e-03 | NA |
| GO:0030126 | COPI vesicle coat | NA | NA | 2.10e-03 | 2.21e-02 |
| GO:0030141 | secretory granule | NA | NA | 2.11e-03 | 1.58e-03 |
| GO:0000779 | condensed chromosome, centromeric region | NA | NA | 2.11e-03 | 1.67e-02 |
| GO:0005784 | Sec61 translocon complex | NA | NA | 2.31e-03 | NA |
| GO:0071256 | translocon complex | NA | NA | 2.31e-03 | NA |
| GO:0005766 | primary lysosome | NA | NA | 2.79e-03 | 2.89e-04 |
| GO:0042582 | azurophil granule | NA | NA | 2.79e-03 | 2.89e-04 |
| GO:0031090 | organelle membrane | NA | NA | 2.79e-03 | 1.62e-02 |
| GO:0030134 | COPII-coated ER to Golgi transport vesic... | NA | NA | 2.91e-03 | 3.14e-05 |
| GO:0012507 | ER to Golgi transport vesicle membrane | NA | NA | 3.43e-03 | 5.36e-04 |
| GO:0099503 | secretory vesicle | NA | NA | 3.43e-03 | 1.17e-03 |
| GO:0032040 | small-subunit processome | NA | NA | 4.98e-03 | 9.71e-03 |
| GO:0019773 | proteasome core complex, alpha-subunit c... | NA | NA | 4.98e-03 | NA |
| GO:0005773 | vacuole | NA | NA | 5.21e-03 | 1.37e-02 |
| GO:0030892 | mitotic cohesin complex | NA | NA | 6.60e-03 | NA |
| GO:0098576 | lumenal side of membrane | NA | NA | 7.46e-03 | 1.91e-03 |
| GO:1904724 | tertiary granule lumen | NA | NA | 8.40e-03 | 4.38e-02 |
| GO:0043231 | intracellular membrane-bounded organelle | NA | NA | 8.50e-03 | 1.35e-02 |
| GO:0019897 | extrinsic component of plasma membrane | NA | NA | 8.50e-03 | 1.85e-02 |
| GO:0031902 | late endosome membrane | NA | NA | 8.85e-03 | NA |
| GO:0043227 | membrane-bounded organelle | NA | NA | 1.00e-02 | 1.94e-02 |
| GO:0009986 | cell surface | NA | NA | 1.08e-02 | NA |
| GO:1905360 | GTPase complex | NA | NA | 1.11e-02 | 1.60e-02 |
| GO:0098797 | plasma membrane protein complex | NA | NA | 1.11e-02 | 4.16e-02 |
| GO:0005787 | signal peptidase complex | NA | NA | 1.12e-02 | NA |
| GO:0030658 | transport vesicle membrane | NA | NA | 1.35e-02 | 4.37e-03 |
| GO:0001940 | male pronucleus | NA | NA | 1.36e-02 | NA |
| GO:0000502 | proteasome complex | NA | NA | 1.39e-02 | 3.02e-02 |
| GO:0035577 | azurophil granule membrane | NA | NA | 1.47e-02 | 6.29e-03 |
| GO:0008250 | oligosaccharyltransferase complex | NA | NA | 1.47e-02 | NA |
| GO:0098588 | bounding membrane of organelle | NA | NA | 1.53e-02 | NA |
| GO:0008278 | cohesin complex | NA | NA | 1.58e-02 | NA |
| GO:0005791 | rough endoplasmic reticulum | NA | NA | 1.58e-02 | 7.95e-03 |
| GO:0051233 | spindle midzone | NA | NA | 1.59e-02 | 1.94e-02 |
| GO:0000940 | outer kinetochore | NA | NA | 1.65e-02 | NA |
| GO:0030669 | clathrin-coated endocytic vesicle membra... | NA | NA | 1.67e-02 | 2.83e-02 |
| GO:1905369 | endopeptidase complex | NA | NA | 1.86e-02 | 4.01e-02 |
| GO:0070161 | anchoring junction | NA | NA | 1.91e-02 | NA |
| GO:1902494 | catalytic complex | NA | NA | 2.39e-02 | NA |
| GO:0034663 | endoplasmic reticulum chaperone complex | NA | NA | 2.42e-02 | 1.21e-02 |
| GO:0030289 | protein phosphatase 4 complex | NA | NA | 2.52e-02 | NA |
| GO:0045277 | respiratory chain complex IV | NA | NA | 2.62e-02 | NA |
| GO:0005794 | Golgi apparatus | NA | NA | 2.71e-02 | NA |
| GO:0005730 | nucleolus | NA | NA | 2.78e-02 | NA |
| GO:0098798 | mitochondrial protein-containing complex | NA | NA | 2.85e-02 | NA |
| GO:0030684 | preribosome | NA | NA | 3.23e-02 | 4.12e-02 |
| GO:0009897 | external side of plasma membrane | NA | NA | 3.29e-02 | NA |
| GO:0005798 | Golgi-associated vesicle | NA | NA | 3.64e-02 | NA |
| GO:0016469 | proton-transporting two-sector ATPase co... | NA | NA | 3.83e-02 | NA |
| GO:0034774 | secretory granule lumen | NA | NA | 4.63e-02 | 3.20e-02 |
| GO:0071007 | U2-type catalytic step 2 spliceosome | NA | NA | 4.73e-02 | 1.94e-02 |
| GO:0030054 | cell junction | NA | NA | 5.00e-02 | NA |
| GO:0005775 | vacuolar lumen | NA | NA | 5.00e-02 | 1.31e-02 |
| GO:0098803 | respiratory chain complex | NA | NA | NA | 2.59e-03 |
| GO:0005793 | endoplasmic reticulum-Golgi intermediate... | NA | NA | NA | 1.97e-02 |
| GO:0034506 | chromosome, centromeric core domain | NA | NA | NA | 2.30e-02 |
| GO:0033116 | endoplasmic reticulum-Golgi intermediate... | NA | NA | NA | 2.35e-02 |
| GO:0008541 | proteasome regulatory particle, lid subc... | NA | NA | NA | 3.02e-02 |
| GO:0031983 | vesicle lumen | NA | NA | NA | 4.10e-02 |
| GO:0060205 | cytoplasmic vesicle lumen | NA | NA | NA | 4.10e-02 |
| GO:0035578 | azurophil granule lumen | NA | NA | NA | 4.38e-02 |
| GO:0043505 | CENP-A containing nucleosome | NA | NA | NA | 4.46e-02 |
| GO:0061638 | CENP-A containing chromatin | NA | NA | NA | 4.46e-02 |
| GO:0030496 | midbody | NA | NA | NA | 4.63e-02 |
| GO:0030867 | rough endoplasmic reticulum membrane | NA | NA | NA | 4.95e-02 |
| GO.ID | Term | positive.PC.1 | negative.PC.1 | positive.PC.2 | negative.PC.2 |
|---|---|---|---|---|---|
| GO:0005768 | endosome | 7.24e-03 | NA | NA | NA |
| GO:0005783 | endoplasmic reticulum | 1.17e-02 | NA | NA | NA |
| GO:0005615 | extracellular space | 1.17e-02 | NA | NA | NA |
| GO:0043230 | extracellular organelle | 1.17e-02 | NA | NA | NA |
| GO:0065010 | extracellular membrane-bounded organelle | 1.17e-02 | NA | NA | NA |
| GO:0070062 | extracellular exosome | 1.17e-02 | NA | NA | NA |
| GO:1903561 | extracellular vesicle | 1.17e-02 | NA | NA | NA |
| GO:0016020 | membrane | 2.39e-02 | NA | NA | NA |
| GO:0071944 | cell periphery | 2.82e-02 | NA | NA | NA |
| GO:0005886 | plasma membrane | 3.44e-02 | NA | NA | NA |
| GO.ID | Term | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 |
|---|---|---|---|---|---|
| GO:0071944 | cell periphery | NA | NA | NA | 4.03e-02 |
| GO:0016020 | membrane | NA | NA | NA | 4.03e-02 |
| GO:0005886 | plasma membrane | NA | NA | NA | 4.84e-02 |
| GO.ID | Term | positive.PC.1 | negative.PC.1 | positive.PC.2 | negative.PC.2 |
|---|---|---|---|---|---|
| GO:0003735 | structural constituent of ribosome | 1.59e-27 | NA | NA | NA |
| GO:0023026 | MHC class II protein complex binding | 2.66e-08 | NA | NA | NA |
| GO:0003924 | GTPase activity | 1.50e-06 | NA | NA | NA |
| GO:0005198 | structural molecule activity | 1.68e-06 | NA | 6.01e-04 | NA |
| GO:0023023 | MHC protein complex binding | 1.92e-06 | NA | NA | NA |
| GO:0140678 | molecular function inhibitor activity | 4.78e-05 | NA | NA | NA |
| GO:0008430 | selenium binding | 1.86e-04 | NA | NA | NA |
| GO:0019001 | guanyl nucleotide binding | 1.86e-04 | NA | NA | NA |
| GO:0032561 | guanyl ribonucleotide binding | 1.86e-04 | NA | NA | NA |
| GO:0042287 | MHC protein binding | 1.87e-04 | NA | NA | NA |
| GO:0005525 | GTP binding | 2.02e-04 | NA | NA | NA |
| GO:0016209 | antioxidant activity | 2.59e-04 | NA | NA | NA |
| GO:0003925 | G protein activity | 2.59e-04 | NA | NA | NA |
| GO:0032395 | MHC class II receptor activity | 2.59e-04 | NA | 6.95e-06 | NA |
| GO:0019003 | GDP binding | 2.59e-04 | NA | NA | NA |
| GO:0019843 | rRNA binding | 2.59e-04 | NA | NA | NA |
| GO:0015078 | proton transmembrane transporter activit... | 4.11e-04 | NA | NA | NA |
| GO:0140375 | immune receptor activity | 4.30e-04 | NA | NA | NA |
| GO:0051920 | peroxiredoxin activity | 5.38e-04 | NA | NA | NA |
| GO:0004857 | enzyme inhibitor activity | 6.56e-04 | NA | NA | NA |
| GO:0042277 | peptide binding | 9.15e-04 | NA | NA | NA |
| GO:0031386 | protein tag activity | 9.15e-04 | NA | NA | NA |
| GO:0141047 | molecular tag activity | 9.15e-04 | NA | NA | NA |
| GO:0004866 | endopeptidase inhibitor activity | 9.15e-04 | NA | NA | NA |
| GO:0031681 | G-protein beta-subunit binding | 9.31e-04 | NA | NA | NA |
| GO:0009055 | electron transfer activity | 9.58e-04 | NA | NA | NA |
| GO:0003823 | antigen binding | 1.15e-03 | NA | 3.04e-02 | NA |
| GO:0061134 | peptidase regulator activity | 1.87e-03 | NA | NA | NA |
| GO:0005102 | signaling receptor binding | 2.28e-03 | NA | NA | NA |
| GO:0016668 | oxidoreductase activity, acting on a sul... | 2.29e-03 | NA | NA | NA |
| GO:0030414 | peptidase inhibitor activity | 2.40e-03 | NA | NA | NA |
| GO:0097177 | mitochondrial ribosome binding | 3.66e-03 | NA | NA | NA |
| GO:0042605 | peptide antigen binding | 3.76e-03 | NA | 7.37e-03 | NA |
| GO:0015453 | oxidoreduction-driven active transmembra... | 3.81e-03 | NA | NA | NA |
| GO:0048027 | mRNA 5'-UTR binding | 5.16e-03 | NA | NA | NA |
| GO:0004601 | peroxidase activity | 5.58e-03 | NA | NA | NA |
| GO:0019763 | immunoglobulin receptor activity | 5.58e-03 | NA | NA | NA |
| GO:0016684 | oxidoreductase activity, acting on perox... | 8.77e-03 | NA | NA | NA |
| GO:0003743 | translation initiation factor activity | 8.77e-03 | NA | NA | NA |
| GO:0008379 | thioredoxin peroxidase activity | 8.77e-03 | NA | NA | NA |
| GO:0140824 | thioredoxin-dependent peroxiredoxin acti... | 8.77e-03 | NA | NA | NA |
| GO:0045296 | cadherin binding | 1.02e-02 | NA | NA | NA |
| GO:0015180 | L-alanine transmembrane transporter acti... | 1.04e-02 | NA | NA | NA |
| GO:0050839 | cell adhesion molecule binding | 1.10e-02 | NA | NA | NA |
| GO:0061650 | ubiquitin-like protein conjugating enzym... | 1.22e-02 | NA | NA | NA |
| GO:0003723 | RNA binding | 1.61e-02 | NA | 1.71e-06 | NA |
| GO:0001671 | ATPase activator activity | 1.77e-02 | NA | NA | NA |
| GO:0061135 | endopeptidase regulator activity | 1.77e-02 | NA | NA | NA |
| GO:0004867 | serine-type endopeptidase inhibitor acti... | 1.77e-02 | NA | NA | NA |
| GO:0098632 | cell-cell adhesion mediator activity | 1.80e-02 | NA | NA | NA |
| GO:0016722 | oxidoreductase activity, acting on metal... | 2.00e-02 | NA | NA | NA |
| GO:0004128 | cytochrome-b5 reductase activity, acting... | 2.29e-02 | NA | NA | NA |
| GO:0015399 | primary active transmembrane transporter... | 2.50e-02 | NA | NA | NA |
| GO:0046933 | proton-transporting ATP synthase activit... | 2.64e-02 | NA | NA | NA |
| GO:0030545 | signaling receptor regulator activity | 2.69e-02 | NA | NA | NA |
| GO:1903136 | cuprous ion binding | 3.23e-02 | NA | NA | NA |
| GO:0055102 | lipase inhibitor activity | 3.23e-02 | NA | NA | NA |
| GO:0042625 | ATPase-coupled ion transmembrane transpo... | 3.42e-02 | NA | NA | NA |
| GO:0044769 | ATPase activity, coupled to transmembran... | 3.42e-02 | NA | NA | NA |
| GO:0046961 | proton-transporting ATPase activity, rot... | 3.42e-02 | NA | NA | NA |
| GO:0042288 | MHC class I protein binding | 3.64e-02 | NA | NA | NA |
| GO:0030527 | structural constituent of chromatin | 3.72e-02 | NA | 2.28e-15 | NA |
| GO:0047134 | protein-disulfide reductase (NAD(P)H) ac... | 3.87e-02 | NA | NA | NA |
| GO:0086080 | protein binding involved in heterotypic ... | 3.91e-02 | NA | NA | NA |
| GO:0042289 | MHC class II protein binding | 3.91e-02 | NA | NA | NA |
| GO:0038023 | signaling receptor activity | 3.91e-02 | NA | NA | NA |
| GO:0060089 | molecular transducer activity | 3.91e-02 | NA | NA | NA |
| GO:0061631 | ubiquitin conjugating enzyme activity | 3.91e-02 | NA | NA | NA |
| GO:0016655 | oxidoreductase activity, acting on NAD(P... | 3.91e-02 | NA | NA | NA |
| GO:0016667 | oxidoreductase activity, acting on a sul... | 3.92e-02 | NA | NA | NA |
| GO:0070851 | growth factor receptor binding | 4.32e-02 | NA | NA | NA |
| GO:0015036 | disulfide oxidoreductase activity | 4.32e-02 | NA | NA | NA |
| GO:0048531 | beta-1,3-galactosyltransferase activity | 4.33e-02 | NA | NA | NA |
| GO:0031625 | ubiquitin protein ligase binding | 4.61e-02 | NA | NA | NA |
| GO:0044389 | ubiquitin-like protein ligase binding | 4.61e-02 | NA | NA | NA |
| GO:0098631 | cell adhesion mediator activity | 4.61e-02 | NA | NA | NA |
| GO:0030346 | protein phosphatase 2B binding | 4.61e-02 | NA | NA | NA |
| GO:0016615 | malate dehydrogenase activity | 4.64e-02 | NA | NA | NA |
| GO:0030546 | signaling receptor activator activity | 4.65e-02 | NA | NA | NA |
| GO:0032393 | MHC class I receptor activity | 4.75e-02 | NA | NA | NA |
| GO:0048018 | receptor ligand activity | 4.82e-02 | NA | NA | NA |
| GO:0051087 | protein-folding chaperone binding | 4.92e-02 | NA | NA | NA |
| GO:0001618 | virus receptor activity | 4.92e-02 | NA | NA | NA |
| GO:0140272 | exogenous protein binding | 4.92e-02 | NA | NA | NA |
| GO:0005524 | ATP binding | NA | 3.45e-18 | NA | NA |
| GO:0030554 | adenyl nucleotide binding | NA | 3.45e-18 | NA | NA |
| GO:0032559 | adenyl ribonucleotide binding | NA | 3.45e-18 | NA | NA |
| GO:0043167 | ion binding | NA | 6.93e-11 | NA | NA |
| GO:0003677 | DNA binding | NA | 6.93e-11 | 9.38e-03 | NA |
| GO:0140993 | histone modifying activity | NA | 1.77e-10 | NA | NA |
| GO:0004386 | helicase activity | NA | 1.17e-09 | NA | NA |
| GO:0030695 | GTPase regulator activity | NA | 2.20e-09 | NA | NA |
| GO:0060589 | nucleoside-triphosphatase regulator acti... | NA | 2.20e-09 | NA | NA |
| GO:0036094 | small molecule binding | NA | 2.20e-09 | NA | NA |
| GO:0016887 | ATP hydrolysis activity | NA | 3.91e-09 | NA | NA |
| GO:0140097 | catalytic activity, acting on DNA | NA | 4.69e-09 | NA | NA |
| GO:0016772 | transferase activity, transferring phosp... | NA | 8.40e-09 | NA | NA |
| GO:0016773 | phosphotransferase activity, alcohol gro... | NA | 9.60e-09 | NA | NA |
| GO:0140657 | ATP-dependent activity | NA | 9.91e-09 | NA | NA |
| GO:0016301 | kinase activity | NA | 1.07e-08 | NA | NA |
| GO:0043168 | anion binding | NA | 1.21e-08 | NA | NA |
| GO:1901363 | heterocyclic compound binding | NA | 1.21e-08 | NA | NA |
| GO:0032553 | ribonucleotide binding | NA | 2.39e-08 | NA | NA |
| GO:0035639 | purine ribonucleoside triphosphate bindi... | NA | 2.74e-08 | NA | NA |
| GO:0005096 | GTPase activator activity | NA | 2.74e-08 | NA | NA |
| GO:0017076 | purine nucleotide binding | NA | 3.35e-08 | NA | NA |
| GO:0032555 | purine ribonucleotide binding | NA | 4.46e-08 | NA | NA |
| GO:0106310 | protein serine kinase activity | NA | 8.68e-08 | NA | NA |
| GO:0000166 | nucleotide binding | NA | 1.35e-07 | NA | NA |
| GO:1901265 | nucleoside phosphate binding | NA | 1.35e-07 | NA | NA |
| GO:0004672 | protein kinase activity | NA | 1.72e-07 | NA | NA |
| GO:0008094 | ATP-dependent activity, acting on DNA | NA | 3.00e-07 | NA | NA |
| GO:0140640 | catalytic activity, acting on a nucleic ... | NA | 3.70e-07 | NA | NA |
| GO:0004674 | protein serine/threonine kinase activity | NA | 3.87e-07 | NA | NA |
| GO:0097159 | organic cyclic compound binding | NA | 4.73e-06 | 4.24e-05 | NA |
| GO:0003682 | chromatin binding | NA | 4.73e-06 | 1.71e-06 | NA |
| GO:0097367 | carbohydrate derivative binding | NA | 6.25e-06 | NA | NA |
| GO:0046872 | metal ion binding | NA | 8.65e-06 | NA | 2.31e-02 |
| GO:0042393 | histone binding | NA | 9.15e-06 | NA | NA |
| GO:0005085 | guanyl-nucleotide exchange factor activi... | NA | 1.08e-05 | NA | NA |
| GO:0044024 | histone H2AS1 kinase activity | NA | 2.16e-05 | NA | NA |
| GO:0140995 | histone H2A kinase activity | NA | 2.16e-05 | NA | NA |
| GO:0035173 | histone kinase activity | NA | 2.46e-05 | NA | NA |
| GO:0140030 | modification-dependent protein binding | NA | 2.74e-05 | NA | NA |
| GO:0043169 | cation binding | NA | 2.91e-05 | NA | 2.03e-02 |
| GO:0017116 | single-stranded DNA helicase activity | NA | 4.25e-05 | NA | NA |
| GO:0003678 | DNA helicase activity | NA | 6.99e-05 | NA | NA |
| GO:0042054 | histone methyltransferase activity | NA | 1.34e-04 | NA | NA |
| GO:0016741 | transferase activity, transferring one-c... | NA | 1.80e-04 | NA | NA |
| GO:0016740 | transferase activity | NA | 2.74e-04 | NA | NA |
| GO:0043565 | sequence-specific DNA binding | NA | 3.24e-04 | NA | NA |
| GO:0008168 | methyltransferase activity | NA | 4.16e-04 | NA | NA |
| GO:0003690 | double-stranded DNA binding | NA | 5.82e-04 | NA | NA |
| GO:0140033 | acetylation-dependent protein binding | NA | 5.82e-04 | NA | NA |
| GO:0140938 | histone H3 methyltransferase activity | NA | 7.06e-04 | NA | NA |
| GO:0003689 | DNA clamp loader activity | NA | 1.05e-03 | NA | NA |
| GO:0070577 | lysine-acetylated histone binding | NA | 1.17e-03 | NA | NA |
| GO:0046976 | histone H3K27 methyltransferase activity | NA | 1.36e-03 | NA | NA |
| GO:0008170 | N-methyltransferase activity | NA | 1.89e-03 | NA | NA |
| GO:0140110 | transcription regulator activity | NA | 2.07e-03 | NA | NA |
| GO:0008276 | protein methyltransferase activity | NA | 2.17e-03 | NA | NA |
| GO:0004445 | inositol-polyphosphate 5-phosphatase act... | NA | 2.43e-03 | NA | NA |
| GO:0008757 | S-adenosylmethionine-dependent methyltra... | NA | 2.77e-03 | NA | NA |
| GO:1990837 | sequence-specific double-stranded DNA bi... | NA | 2.99e-03 | NA | NA |
| GO:0016279 | protein-lysine N-methyltransferase activ... | NA | 3.04e-03 | NA | NA |
| GO:0140999 | histone H3K4 trimethyltransferase activi... | NA | 3.73e-03 | NA | NA |
| GO:0008381 | mechanosensitive monoatomic ion channel ... | NA | 4.77e-03 | NA | NA |
| GO:0051020 | GTPase binding | NA | 5.18e-03 | NA | NA |
| GO:0043138 | 3'-5' DNA helicase activity | NA | 5.42e-03 | NA | NA |
| GO:0031267 | small GTPase binding | NA | 5.47e-03 | NA | NA |
| GO:0140034 | methylation-dependent protein binding | NA | 6.55e-03 | NA | NA |
| GO:0035091 | phosphatidylinositol binding | NA | 6.78e-03 | NA | NA |
| GO:0016278 | lysine N-methyltransferase activity | NA | 8.79e-03 | NA | NA |
| GO:0035064 | methylated histone binding | NA | 8.79e-03 | NA | NA |
| GO:0004683 | calcium/calmodulin-dependent protein kin... | NA | 1.08e-02 | NA | NA |
| GO:0140947 | histone H3K9me2 methyltransferase activi... | NA | 1.11e-02 | NA | NA |
| GO:0099094 | ligand-gated monoatomic cation channel a... | NA | 1.11e-02 | NA | NA |
| GO:0046030 | inositol trisphosphate phosphatase activ... | NA | 1.44e-02 | NA | NA |
| GO:0003676 | nucleic acid binding | NA | 1.45e-02 | 1.71e-06 | NA |
| GO:0000976 | transcription cis-regulatory region bind... | NA | 1.56e-02 | NA | NA |
| GO:0001067 | transcription regulatory region nucleic ... | NA | 1.58e-02 | NA | NA |
| GO:0008186 | ATP-dependent activity, acting on RNA | NA | 1.60e-02 | NA | NA |
| GO:0022836 | gated channel activity | NA | 1.69e-02 | NA | NA |
| GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphata... | NA | 1.74e-02 | NA | NA |
| GO:0005272 | sodium channel activity | NA | 1.84e-02 | NA | NA |
| GO:0009374 | biotin binding | NA | 2.00e-02 | NA | NA |
| GO:0003724 | RNA helicase activity | NA | 2.00e-02 | NA | NA |
| GO:0003712 | transcription coregulator activity | NA | 2.00e-02 | NA | NA |
| GO:0003995 | acyl-CoA dehydrogenase activity | NA | 2.38e-02 | NA | NA |
| GO:0052890 | oxidoreductase activity, acting on the C... | NA | 2.38e-02 | NA | NA |
| GO:0015276 | ligand-gated monoatomic ion channel acti... | NA | 2.70e-02 | NA | NA |
| GO:0022834 | ligand-gated channel activity | NA | 2.84e-02 | NA | NA |
| GO:0140658 | ATP-dependent chromatin remodeler activi... | NA | 2.99e-02 | NA | NA |
| GO:0016706 | 2-oxoglutarate-dependent dioxygenase act... | NA | 3.28e-02 | NA | NA |
| GO:0003824 | catalytic activity | NA | 3.52e-02 | NA | NA |
| GO:0051011 | microtubule minus-end binding | NA | 3.52e-02 | NA | NA |
| GO:0032135 | DNA insertion or deletion binding | NA | 3.52e-02 | NA | NA |
| GO:0009008 | DNA-methyltransferase activity | NA | 3.59e-02 | NA | NA |
| GO:0043139 | 5'-3' DNA helicase activity | NA | 4.13e-02 | NA | NA |
| GO:0016627 | oxidoreductase activity, acting on the C... | NA | 4.19e-02 | NA | 2.31e-02 |
| GO:0005003 | ephrin receptor activity | NA | 4.39e-02 | NA | NA |
| GO:0000146 | microfilament motor activity | NA | 4.46e-02 | NA | NA |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | NA | 4.46e-02 | NA | NA |
| GO:0071889 | 14-3-3 protein binding | NA | 4.46e-02 | NA | NA |
| GO:0015280 | ligand-gated sodium channel activity | NA | 4.46e-02 | NA | NA |
| GO:0004016 | adenylate cyclase activity | NA | 4.51e-02 | NA | NA |
| GO:0031418 | L-ascorbic acid binding | NA | 4.75e-02 | NA | NA |
| GO:0008289 | lipid binding | NA | 4.89e-02 | NA | NA |
| GO:0046982 | protein heterodimerization activity | NA | NA | 2.14e-04 | NA |
| GO:0008009 | chemokine activity | NA | NA | 1.43e-03 | NA |
| GO:0008017 | microtubule binding | NA | NA | 3.16e-03 | NA |
| GO:0031492 | nucleosomal DNA binding | NA | NA | 3.16e-03 | NA |
| GO:0017111 | ribonucleoside triphosphate phosphatase ... | NA | NA | 3.16e-03 | NA |
| GO:0005515 | protein binding | NA | NA | 9.11e-03 | NA |
| GO:0016817 | hydrolase activity, acting on acid anhyd... | NA | NA | 1.07e-02 | NA |
| GO:0016818 | hydrolase activity, acting on acid anhyd... | NA | NA | 1.07e-02 | NA |
| GO:0016462 | pyrophosphatase activity | NA | NA | 1.19e-02 | NA |
| GO:0003697 | single-stranded DNA binding | NA | NA | 2.31e-02 | NA |
| GO:0015631 | tubulin binding | NA | NA | 4.37e-02 | NA |
| GO:0008301 | DNA binding, bending | NA | NA | 4.61e-02 | NA |
| GO.ID | Term | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 |
|---|---|---|---|---|---|
| GO:0005096 | GTPase activator activity | 3.42e-02 | NA | NA | NA |
| GO:0016772 | transferase activity, transferring phosp... | NA | 3.19e-04 | NA | NA |
| GO:0036094 | small molecule binding | NA | 1.52e-03 | NA | NA |
| GO:0030554 | adenyl nucleotide binding | NA | 1.52e-03 | NA | NA |
| GO:0043167 | ion binding | NA | 1.52e-03 | NA | NA |
| GO:0043169 | cation binding | NA | 1.72e-03 | NA | NA |
| GO:0016301 | kinase activity | NA | 1.72e-03 | NA | NA |
| GO:0046872 | metal ion binding | NA | 2.53e-03 | NA | NA |
| GO:0005524 | ATP binding | NA | 6.01e-03 | NA | NA |
| GO:0032559 | adenyl ribonucleotide binding | NA | 6.01e-03 | NA | NA |
| GO:0016773 | phosphotransferase activity, alcohol gro... | NA | 8.64e-03 | NA | NA |
| GO:0140947 | histone H3K9me2 methyltransferase activi... | NA | 1.27e-02 | NA | NA |
| GO:0016627 | oxidoreductase activity, acting on the C... | NA | 3.19e-02 | NA | NA |
| GO:0005543 | phospholipid binding | NA | 3.19e-02 | NA | NA |
| GO:0003735 | structural constituent of ribosome | NA | NA | 4.00e-15 | 4.61e-13 |
| GO:0030527 | structural constituent of chromatin | NA | NA | 1.96e-10 | 2.82e-10 |
| GO:0005198 | structural molecule activity | NA | NA | 2.47e-08 | 1.61e-09 |
| GO:0003924 | GTPase activity | NA | NA | 1.60e-07 | 1.03e-03 |
| GO:0003723 | RNA binding | NA | NA | 4.93e-07 | 3.29e-06 |
| GO:0003823 | antigen binding | NA | NA | 7.50e-05 | 1.62e-02 |
| GO:0003925 | G protein activity | NA | NA | 7.50e-05 | 3.97e-03 |
| GO:0023026 | MHC class II protein complex binding | NA | NA | 1.38e-04 | 2.89e-03 |
| GO:0019001 | guanyl nucleotide binding | NA | NA | 1.38e-04 | 3.58e-03 |
| GO:0032561 | guanyl ribonucleotide binding | NA | NA | 1.38e-04 | 3.58e-03 |
| GO:0042605 | peptide antigen binding | NA | NA | 2.21e-04 | 3.97e-03 |
| GO:0005525 | GTP binding | NA | NA | 2.21e-04 | 4.20e-03 |
| GO:0019843 | rRNA binding | NA | NA | 3.89e-04 | 3.32e-03 |
| GO:0046982 | protein heterodimerization activity | NA | NA | 4.55e-04 | 2.02e-05 |
| GO:0023023 | MHC protein complex binding | NA | NA | 7.93e-04 | 3.30e-03 |
| GO:0042287 | MHC protein binding | NA | NA | 1.02e-03 | 1.14e-02 |
| GO:0019003 | GDP binding | NA | NA | 1.34e-03 | 9.12e-03 |
| GO:0048027 | mRNA 5'-UTR binding | NA | NA | 1.41e-03 | 4.20e-03 |
| GO:0005126 | cytokine receptor binding | NA | NA | 1.41e-03 | NA |
| GO:0032395 | MHC class II receptor activity | NA | NA | 1.43e-03 | 2.78e-02 |
| GO:0005515 | protein binding | NA | NA | 4.21e-03 | 9.12e-03 |
| GO:0140678 | molecular function inhibitor activity | NA | NA | 4.34e-03 | NA |
| GO:0045296 | cadherin binding | NA | NA | 5.36e-03 | 2.47e-02 |
| GO:0050839 | cell adhesion molecule binding | NA | NA | 8.86e-03 | NA |
| GO:0003743 | translation initiation factor activity | NA | NA | 8.86e-03 | 2.96e-02 |
| GO:0061134 | peptidase regulator activity | NA | NA | 9.17e-03 | 4.30e-02 |
| GO:0004576 | oligosaccharyl transferase activity | NA | NA | 9.17e-03 | NA |
| GO:0004579 | dolichyl-diphosphooligosaccharide-protei... | NA | NA | 9.17e-03 | NA |
| GO:0140375 | immune receptor activity | NA | NA | 1.05e-02 | NA |
| GO:0004857 | enzyme inhibitor activity | NA | NA | 1.16e-02 | NA |
| GO:0098632 | cell-cell adhesion mediator activity | NA | NA | 1.43e-02 | NA |
| GO:0008009 | chemokine activity | NA | NA | 1.74e-02 | 4.30e-02 |
| GO:0090079 | translation regulator activity, nucleic ... | NA | NA | 1.79e-02 | NA |
| GO:0045182 | translation regulator activity | NA | NA | 1.99e-02 | NA |
| GO:0042379 | chemokine receptor binding | NA | NA | 2.25e-02 | NA |
| GO:0042277 | peptide binding | NA | NA | 2.55e-02 | NA |
| GO:0031386 | protein tag activity | NA | NA | 2.59e-02 | NA |
| GO:0141047 | molecular tag activity | NA | NA | 2.59e-02 | NA |
| GO:0010854 | adenylate cyclase regulator activity | NA | NA | 2.59e-02 | NA |
| GO:0046977 | TAP binding | NA | NA | 2.59e-02 | NA |
| GO:0051920 | peroxiredoxin activity | NA | NA | 2.67e-02 | NA |
| GO:0008135 | translation factor activity, RNA binding | NA | NA | 2.71e-02 | NA |
| GO:0086080 | protein binding involved in heterotypic ... | NA | NA | 3.14e-02 | NA |
| GO:0004791 | thioredoxin-disulfide reductase (NADPH) ... | NA | NA | 3.25e-02 | NA |
| GO:0046983 | protein dimerization activity | NA | NA | 3.25e-02 | NA |
| GO:0016668 | oxidoreductase activity, acting on a sul... | NA | NA | 3.25e-02 | NA |
| GO:0016209 | antioxidant activity | NA | NA | 3.69e-02 | NA |
| GO:0008375 | acetylglucosaminyltransferase activity | NA | NA | 3.72e-02 | NA |
| GO:0043024 | ribosomal small subunit binding | NA | NA | 3.99e-02 | NA |
| GO:0016504 | peptidase activator activity | NA | NA | 4.10e-02 | NA |
| GO:0005102 | signaling receptor binding | NA | NA | 4.85e-02 | NA |
| GO:0005125 | cytokine activity | NA | NA | NA | 1.62e-02 |
| GO.ID | Term | positive.PC.1 | negative.PC.1 | positive.PC.2 | negative.PC.2 |
|---|---|---|---|---|---|
| GO:0038023 | signaling receptor activity | 2.74e-03 | NA | NA | NA |
| GO:0060089 | molecular transducer activity | 2.74e-03 | NA | NA | NA |
| GO:0004888 | transmembrane signaling receptor activit... | 2.74e-03 | NA | NA | NA |
| GO:0140096 | catalytic activity, acting on a protein | NA | NA | 4.63e-02 | NA |
| GO.ID | Term | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 |
|---|---|---|---|---|---|
| GO:0038023 | signaling receptor activity | NA | 1.42e-02 | NA | 4.38e-03 |
| GO:0060089 | molecular transducer activity | NA | 1.42e-02 | NA | 4.38e-03 |
| GO:0140096 | catalytic activity, acting on a protein | NA | 2.02e-02 | NA | 3.26e-02 |
| GO:0004888 | transmembrane signaling receptor activit... | NA | 2.76e-02 | NA | 1.33e-02 |
| final_main_params | |
|---|---|
| model_organism | Human |
| annot_table | NULL |
| input_gene_id | ENSEMBL |
| custom | NULL |
| enrich_dbs | c("Reactome", "KEGG", "BP", "CC", "MF") |
| kegg_data_file | /Users/marmtnez/Desktop/Master_Bioinfo/TFM/installed_software/ExpHunterSuite/inst/scripts/../../inst/kegg_data_files/hsa_KEGG.rds |
| enrich_methods | ORA |
| annotation_source | orgdb |
| pthreshold | 0.1 |
| qthreshold | 0.2 |
| cores | 1 |
| task_size | 10 |
| output_files | /Users/marmtnez/Desktop/Master_Bioinfo/TFM/Results/functional/opg_vs_gtdup_fe |
| fc_colname | mean_logFCs |
| universe | NULL |
| clean_parentals | FALSE |
| simplify | FALSE |
| top_categories | 50 |
| sim_thr | NULL |
| summary_common_name | ancestor |
| clusters_flag | TRUE |